Results 271 to 280 of about 84,247 (372)

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

RETRACTION: Association Between Cathepsins and Skin Cancers: A Bidirectional Two-Sample Mendelian Randomization Study. [PDF]

Skin Res Technol
europepmc   +1 more source

Mendelian Randomization Analyses Reveal the Causal Effect of Cathepsin Z on the Risk of Different Subtypes of Thyroid Cancer. [PDF]

Int J Endocrinol
Sun SK, Yuan JL.
europepmc   +1 more source

Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.

, 1993
Eric T. Baldwin, Talapady N. Bhat, Sergei Gulnik, M.V. Hosur, Raymond C. Sowder, Raúl E. Cachau, Jack Collins, A M Silva, John W. Erickson   +8 more
openalex   +2 more sources

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Altered Transcriptome Signature in Primary Human Myotubes Exposed to Inclusion Body Myositis Serum: A Pilot Case Comparison of Anti-cN1A Positive and Negative Sera. [PDF]

Muscles
Slater N, Chopra A, Ram R, Adams A, Mastaglia FL, Needham M, Coudert JD.   +6 more
europepmc   +1 more source

Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser

, 2012
Lars Redecke, Karol Nass, Daniel P. DePonte, Thomas A. White, D. Rehders, Anton Barty, Francesco Stellato, Mengning Liang, T.R.M. Barends, Sébastien Boutet, Garth J. Williams, M. Messerschmidt, M. Seibert, Andrew Aquila, David Arnlund, S. Bajt, Torsten Barth, Michael J. Bogan, Carl Caleman, Tzu‐Chiao Chao, R. Bruce Doak, Holger Fleckenstein, Matthias Frank, Raimund Fromme, Lorenzo Galli, Ingo Grotjohann, Mark S. Hunter, Linda C. Johansson, Stephan Kassemeyer, Gergely Katona, Richard A. Kirian, Rudolf Koopmann, Chris Kupitz, Lukas Lomb, Andrew V. Martin, Stefan Mogk, Richard Neutze, Robert L. Shoeman, Jan Steinbrener, Nicuşor Tı̂mneanu, Dingjie Wang, Uwe Weierstall, Nadia A. Zatsepin, John C. H. Spence, Petra Fromme, Ilme Schlichting, Michael Duszenko, Christian Betzel, Henry N. Chapman   +48 more
openalex   +2 more sources

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source

Potential of Proteases in the Diagnosis of Bladder Cancer. [PDF]

Cancers (Basel)
Guszcz T, Lukaszewski Z, Gorodkiewicz E, Hermanowicz A.   +3 more
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source