Results 251 to 260 of about 51,705 (353)

Lysosomal protease-mediated APP degradation is pH-dependent, mutation-sensitive, and facilitates tau proteolysis. [PDF]

Mol Neurodegener Adv
Ackley C, Liau Z, Arya S, Antee T, Cheang E, Knudsen GM, Lane-Donovan C, Sampognaro PJ, Kao AW.   +8 more
europepmc   +1 more source

Targeting Glycolysis with 2-Deoxy-D-Glucose and Lysosomal Integrity with L-Leucyl-L-Leucine Methyl Ester as Antimelanoma Strategy. [PDF]

Pharmaceutics
Kosic M, Bosnjak M, Mandic M, Vucicevic L, Marjanovic MM, Poulsen SE, Harhaji-Trajkovic L.   +6 more
europepmc   +1 more source

CATHEPSIN B PLAY A CRITICAL ROLE IN AMYLOID β INFLUX VIA CEREBRAL ENDOTHELIAL CELLS DURING PORPHYROMONAS GINGIVALIS INFECTION [PDF]

Shuge Gui, Zeng Fan, Yicong Liu, Junjun Ni, Zhou Wu   +4 more
openalex   +1 more source

Changing landscape of optical imaging in skeletal metastases [PDF]

, 2019
Cho, Nicholas, Shokeen, Monica
core   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Causal association between cathepsins and asthma: a Mendelian randomization study. [PDF]

Sci Rep
Qiu F, Shao W, Qin X, Xu R, Liu Y, Lu H.
europepmc   +1 more source

Pathobiochemical mechanisms leading to acquired coagulation defects [PDF]

, 1985
Duswald, Karl-Heimo, Fritz, Hans, Jochum, Marianne, Schmid-Schönbein, H., Wurzinger, L. J., Zimmermann, R. E.   +5 more
core  

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Intralysosomal pathogens differentially influence the proteolytic potential of their niche. [PDF]

Infect Immun
Bird LE, Xu B, Thomas DR, McGowan ENS, Newton P, Scott NE, McConville MJ, Edgington-Mitchell LE, Newton HJ.   +8 more
europepmc   +1 more source

Homology of amino acid sequences of rat liver cathepsins B and H with that of papain.

, 1983
Koji Takio, Takae Towatari, Nobuhiko Katunuma, D.C. Teller, Koiti Titani   +4 more
openalex   +2 more sources