Results 111 to 120 of about 3,347 (210)

Effects of khat ethanol extract, cathinone and cathine on cytochrome P450 activities in vitro, molecular docking CYP-cathinone and CYP-cathine interactions and in vivo effects on Caenorhabditis elegans [PDF]

open access: yes
Khat (Catha edulis Forsk), a natural amphetamine-like psychostimulant plant, and its major active compounds cathinone and cathine are consumed by many not only for cultural practice but also for its appetite suppressing effects and often co-abused with ...
Lim, Sharoen Yu Ming
core   +4 more sources

Pyrrylphenylethanones Related to Cathinone and Lefetamine : Synthesis and Pharmacological Activities.

open access: yes, 1992
The synthesis of various pyrrylphenylethanones resembling cathinone and lefetamine is described starting from 2-chloro-1-(1-methyl-1H-pyrrol-2-yl)-2-phenylethan-1-one.
PANTALEONI G. C   +6 more
core   +1 more source

Prolonged analgesia induced by cathinone. The role of stress and opioid and nonopioid mechanisms

open access: yes, 1984
Cathinone, the active principle of Catha edulis (khat), shows long-lasting analgesic effects when the tail-flick test is used in rats. The involvement of monoamines, endogeneous opioids and stress in this analgesic effect was tested.
A. M. Ahmed   +4 more
core  

Naloxone-reversible antinociceptive activity of cathinone, the active principle of khat, in the mouse and rat

open access: yes, 1982
The analgesic activity of cathinone, an amphetamine-like agent considered as the major active principle of khat, was studied on three different nociceptive models.
A. M. Ahmed, NENCINI, Paolo
core  

The Interaction of Instrumental as Well as Stimulus Risk Propensity and the Use of Cathinone Derivatives in Early Adulthood. The Mediating Role of Mental Resilience

open access: yesLubelski Rocznik Pedagogiczny
Introduction: The period of entering adulthood, constituting the transition between adolescence and early adulthood, for many young adults and their families involves a number of developmental tasks and crises that they face.
Marta Pięta-Chrystofiak, Damian Brohs
doaj   +1 more source

EMCDDA Framework for Naming Cathinones

open access: yesEmerging Trends in Drugs, Addictions, and Health
Introduction: The short names attributed to the 170 cathinones monitored by the EMCDDA are only loosely associated with structural features. Although related to the parent compound cathinone, one of the psychoactive principals in khat, attributing ...
B. Pulver   +3 more
doaj   +1 more source

Low Configurational Stability of Amfepramone and Cathinone - Mechanism and Kinetics of Chiral Inversion

open access: yes, 1995
The low configurational stability of two model compounds, the anorectic drug amfepramone and one of its basic metabolites, rac-cathinone, was examined for its mechanism and kinetics.
Testa, Bernard   +4 more
core   +1 more source

Neurotoxicity of Synthetic Cathinones

open access: yesPostepy biochemii, 2023
Synthetic cathinones are the group of the most frequently identified so-called new psychoactive substances with a strong stimulating effect and high addictive potential. It is now believed that the use of these compounds increases the risk of sporadic forms of neurodegenerative diseases.
openaire   +1 more source

Identification of a Novel Synthetic Cathinone CMMP

open access: yes
ObjectiveTo establish a method to identify an unknown substance based on the combined use of gas chromatography-quadrupole time-of-flight mass spectrometry (GC-QTOF-MS), ultra-high performance liquid chromatography-quadrupole/electrostatic field orbitrap
HE Si-yang   +7 more
core   +1 more source

Neuropharmacological properties of the cathinones

open access: yes, 2015
At the height of its popularity, mephedrone was the most common recreationally used cathinone. This is thought to be due to its perceived likeness to MDMA. Therefore the aim of this thesis was to examine mephedrone-induced changes in behaviour, body temperature or neurochemistry in the rat and to compare these changes to those observed following MDMA ...
openaire   +2 more sources

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