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Potentiation of cathinone by caffeine and nikethamide
Pharmacology Biochemistry and Behavior, 1989The drug discrimination paradigm was employed to evaluate the effect of coadministration of both caffeine and nikethamide upon the discrimination of a low dose of cathinone. In rats trained to discriminate between 0.8 mg/kg l-cathinone and its vehicle in a two-lever food-motivated operant task, 0.2 mg/kg cathinone produced 29.2% of responses on the ...
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Chemsex and cathinones« Chemsex » et cathinones
International ...Alvarez, Jean Claude +1 more
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The pharmacology and neurotoxicology of synthetic cathinones
The synthetic cathinones are man-made compounds derived from the naturally occurring drug cathinone, which is found in the khat plant. The drugs in this pharmacological class that will be the focus of this chapter include mephedrone, MDPV, methcathinone and methylone. These drugs are colloquially known as "bath salts". This misnomer suggests that theseMariana, Angoa-Perez, Donald M, Kuhn
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L'Encephale, 2017
The pattern of recreational drug use has changed over the last decade and now includes a multitude of substances sold as "research chemicals" or new psychoactive substances, "NPS". In France, synthetic cathinones emerged in 2008 (while first mentioned by the French police force in 2007 first alerts among users appeared in 2008) and have grown to be ...
A, Batisse +4 more
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The pattern of recreational drug use has changed over the last decade and now includes a multitude of substances sold as "research chemicals" or new psychoactive substances, "NPS". In France, synthetic cathinones emerged in 2008 (while first mentioned by the French police force in 2007 first alerts among users appeared in 2008) and have grown to be ...
A, Batisse +4 more
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Naturally Occurring Cathinone from Khat, Synthetic Cathinones, and Cytochrome P450
2022Sharoen Yu Ming Lim +3 more
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Metabolism of Synthetic Cathinones
2018Synthetic cathinones have recently emerged and are abused worldwide. To date, numerous cathinone derivatives have been identified as new psychoactive substances, and their chemical structures have gradually become complicated. Accordingly, metabolic pathways of synthetic cathinones differ depending on their chemical structures, and forensic ...
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