Results 161 to 170 of about 17,019 (205)

Fabry Cardiomyopathy: Myocardial Fibrosis, Inflammation, and Down-Regulation of Mannose-6-Phosphate Receptors Cause Low Accessibility to Enzyme Replacement Therapy. [PDF]

J Am Heart Assoc
Frustaci A, Verardo R, Magnocavallo M, Frustaci E, Russo MA, Chimenti C.   +5 more
europepmc   +1 more source

The Alzheimer's Disease Gene SORL1 Regulates Lysosome Function in Human Microglia. [PDF]

Glia
Mishra S, Morshed N, Sidhu SB, Kinoshita C, Stevens B, Jayadev S, Young JE.   +6 more
europepmc   +1 more source

Disruption of Man-6-P-Dependent Sorting to Lysosomes Confers IGF1R-Mediated Apoptosis Resistance. [PDF]

Int J Mol Sci
Aynaci A, Toussaint M, Gilis F, Albert M, Gaussin JF, Jadot M, Boonen M.   +6 more
europepmc   +1 more source

The Parkinson Disease-Associated Mutant DNAJC13(N855S) Leads to Its Accelerated Degradation and Negatively Affects Macroautophagy and Retromer Complex-Mediated Dynamics. [PDF]

J Cell Physiol
Stein A, Vo S, Freese C, Kluge J, Maus J, Koziollek-Drechsler I, Silva B, Behl C, Clement AM.   +8 more
europepmc   +1 more source

Disruption of Retriever Function Impacts Retrograde Trafficking From Endosomes. [PDF]

Cell Biol Int
Li Z, Yang Z, Teasdale RD.
europepmc   +1 more source

Bacterial Adaptation to Stress Induced by Glyoxal/Methylglyoxal and Advanced Glycation End Products. [PDF]

Microorganisms
Kuczyńska-Wiśnik D, Stojowska-Swędrzyńska K, Laskowska E.   +2 more
europepmc   +1 more source

Arylsulfatase B induces melanoma apoptosis by the ubiquitin ligase COP1. [PDF]

J Biol Chem
Bhattacharyya S, O-Sullivan I, Whiteley HE, Yang J, Zhang F, Tobacman JK.   +5 more
europepmc   +1 more source

PGRN as an emerging regulator of lipid metabolism in neurodegenerative diseases. [PDF]

Commun Biol
Shi Y, Hou W, Li B, Zhu C.
europepmc   +1 more source

Ion toxicity in waterlogged soils: mechanisms of root response and adaptive strategies. [PDF]

Front Plant Sci
Zhang L, Li Y, Wang Y, Liu Z, Kronzucker HJ, Wang Z, Shi W, Li G.   +7 more
europepmc   +1 more source

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Human DNase I Contains Mannose 6-Phosphate and Binds the Cation-Independent Mannose 6-Phosphate Receptor

Biochemistry, 1998
DNase I isolated from human urine (hDNase) or expressed in Chinese hamster ovary (CHO) cells contains mannose-phosphorylated oligosaccharides. hDNase binds to a column of immobilized cation-independent mannose 6-phosphate receptor, with the strongest binding exhibited by the protein bearing diphosphorylated oligosaccharides. The binding is inhibited by
J, Cacia, C P, Quan, R, Pai, J, Frenz
openaire   +2 more sources