Results 91 to 100 of about 2,178,073 (385)

Pancreatitis in Cats

Topics in Companion Animal Medicine, 2012
Pancreatitis was considered a rare disease in the cat until a couple of decades ago when several retrospective studies of severe acute pancreatitis were published. It was apparent that few of the diagnostic tests of value in the dog were helpful in cats.
P. Jane Armstrong, David A. Williams
openaire   +3 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Estimation of the dietary nutrient profile of free-roaming feral cats: possible implications for nutrition of domestic cats [PDF]

, 2011
Cats are strict carnivores and in the wild rely on a diet solely based on animal tissues to meet their specific and unique nutritional requirements. Although the feeding ecology of cats in the wild has been well documented in the literature, there is no ...
Bosch, G., Hendriks, W.H., Plantinga, E.A.   +2 more
core   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Integrating Trap-Neuter-Return Campaigns Into a Social Framework: Developing Long-Term Positive Behavior Change Toward Unowned Cats in Urban Areas

Frontiers in Veterinary Science, 2018
Cat management is often discussed in terms of population reduction, with trap-neuter-return (TNR) campaigns commonly organized to manage unowned urban cat populations.
Jennifer L. McDonald, Jennifer L. McDonald, Mark J. Farnworth, Jane Clements   +3 more
doaj   +1 more source

The Taming of the Cat

Scientific American, 2009
Unlike other domesticated creatures, the house cat contributes little to human survival. Researchers have therefore wondered how and why cats came to live among people. Experts traditionally thought that the Egyptians were the first to domesticate the cat, some 3,600 years ago.
Driscoll, Carlos A., Clutton-Brock, Juliet, Kitchener, Andrew C., O'Brien, Stephen J.   +3 more
openaire   +2 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Unravelling the spatial properties of individual mobility patterns using longitudinal travel data

Journal of Urban Mobility, 2022
The analysis of longitudinal travel data enables investigating how mobility patterns vary across the population and identify the spatial properties thereof.
Oded Cats, Francesco Ferranti
doaj  

4090 Dysregulation of Skeletal Muscle Mitochondrial Function following Critical Illness: a Translational Approach

Journal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: The objective of the study was to determine whether CLP altered genes associated with mitochondrial function in the diaphragm. METHODS/STUDY POPULATION: A rodent cecal-ligation and puncture (CLP) model used to mimic sepsis-induced ...
Luther Gill, Liz Simon, Patricia Molina
doaj   +1 more source

The Dragon Reaches the Eastern Mediterranean: Why the Region Matters to China

Comparative Southeast European Studies, 2022
The Eastern Mediterranean region has been the subject of global power competition for many decades. Europe, Russia, and the United States have at different stages and in changing configurations sought to exercise influence in and power over various ...
Bastian Jens
doaj   +1 more source