Results 41 to 50 of about 847,673 (362)

Amino acid changes in the spike protein of feline coronavirus correlate with systemic spread of virus from the intestine and not with feline infectious peritonitis [PDF]

, 2014
Recent evidence suggests that a mutation in the spike protein gene of feline coronavirus (FCoV), which results in an amino acid change from methionine to leucine at position 1058, may be associated with feline infectious peritonitis (FIP).
Day, Michael J, Harley, Ross, Helps, Christopher R, Kipar, Anja, Porter, Emily L, Siddell, Stuart G, Tasker, Séverine   +6 more
core   +5 more sources

Prevalence of Gastroesophageal Reflux in Cats During Anesthesia and Effect of Omeprazole on Gastric pH. [PDF]

, 2017
BackgroundGastroesophageal reflux (GER) is poorly characterized in anesthetized cats, but can cause aspiration pneumonia, esophagitis, and esophageal stricture formation.ObjectiveTo determine whether pre-anesthetic orally administered omeprazole ...
Belafsky, PC, Della Maggiore, A, Fulton, A, Garcia, RS, Marks, SL, Osborn, JM, Pierce, T, Pypendop, BH, Walker, VJ   +8 more
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Factors influencing the relationship between the dose of amlodipine required for blood pressure control and change in blood pressure in hypertensive cats [PDF]

, 2016
BACKGROUND: Hypertension is a common problem in elderly cats. In most cats, systolic blood pressure (SBP) of
Bijsmans, E S, Doig, M, Elliott, J, Jepson, R E, Pelligand, L, Syme, H M   +5 more
core   +2 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Ecological modeling, biogeography, and phenotypic analyses setting the tiger cats’ hyperdimensional niches reveal a new species

Scientific Reports
Recently, the tiger-cat species complex was split into Leopardus tigrinus and Leopardus guttulus, along with other proposed schemes. We performed a detailed analysis integrating ecological modeling, biogeography, and phenotype of the four originally ...
Tadeu G. de Oliveira, Lester A. Fox-Rosales, José D. Ramírez-Fernández, Juan C. Cepeda-Duque, Rebecca Zug, Catalina Sanchez-Lalinde, Marcelo J. R. Oliveira, Paulo H. D. Marinho, Alejandra Bonilla-Sánchez, Mara C. Marques, Katia Cassaro, Ricardo Moreno, Damián Rumiz, Felipe B. Peters, Josué Ortega, Gitana Cavalcanti, Michael S. Mooring, Steven R. Blankenship, Esteban Brenes-Mora, Douglas Dias, Fábio D. Mazim, Eduardo Eizirik, Jaime L. Diehl, Rosane V. Marques, Ana Carolina C. Ribeiro, Reginaldo A. Cruz, Emanuelle Pasa, Lyse P. C. Meira, Alex Pereira, Guilherme B. Ferreira, Fernando F. de Pinho, Liana M. M. Sena, Vinícius R. de Morais, Micheli Ribeiro Luiz, Vitor E. C. Moura, Marina O. Favarini, Karla P. G. Leal, Paulo G. C. Wagner, Maurício C. dos Santos, James Sanderson, Elienê P. Araújo, Flávio H. G. Rodrigues   +41 more
doaj   +1 more source

The detection of capsaicin and dihydrocapsaicin in horse serum following long-term local administration

BMC Veterinary Research, 2018
Background Capsaicin and dihydrocapsaicin are alkaloids with analgesic effects in humans and animals. When used locally, both of them minimalise pain sensation by defunctionalising nerve endings.
A. Zak, N. Siwinska, M. Slowikowska, H. Borowicz, P. Szpot, M. Zawadzki, A. Niedzwiedz   +6 more
doaj   +1 more source

Characterization of the fecal microbiome in cats with inflammatory bowel disease or alimentary small cell lymphoma. [PDF]

, 2019
Feline chronic enteropathy (CE) is a common gastrointestinal disorder in cats and mainly comprises inflammatory bowel disease (IBD) and small cell lymphoma (SCL).
Ackermann, Mark R, Chow, Betty, Estep, J Scot, Hill, Steve L, Lidbury, Jonathan A, Marsilio, Sina, Pilla, Rachel, Sarawichitr, Benjamin, Steiner, Joerg M, Suchodolski, Jan S   +9 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source