Results 71 to 80 of about 857,255 (359)

In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease. [PDF]

open access: yes, 2018
BackgroundLiver disease (LD) prolongs mirtazapine half-life in humans, but it is unknown if this occurs in cats with LD and healthy cats.Hypothesis/objectivesTo determine pharmacokinetics of administered orally mirtazapine in vivo and in vitro (liver ...
Benson, Kellyi K   +6 more
core  

Prevalence and co-infection of Toxoplasma gondii and Neospora caninum in Apodemus sylvaticus in an area relatively free of cats [PDF]

open access: yes, 2011
The protozoan parasite Toxoplasma gondii is prevalent worldwide and can infect a remarkably wide range of hosts despite felids being the only definitive host.
A. P. COX   +17 more
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Domestic cat management in the UK: learnings from a global perspective

open access: yesFrontiers in Veterinary Science
The overpopulation of domestic cats has the potential to result in negative outcomes for cats, people and the surrounding environment. A whole-population approach to management requires a system of services considering owned, shelter and free-living ...
Jenni L. McDonald   +5 more
doaj   +1 more source

Searching for ivermectin resistance in a Strongylidae population of horses stabled in Poland

open access: yesBMC Veterinary Research, 2017
Background There are no available studies describing the possible resistance of strongyles to ivermectin in horses in Poland. One hundred seventy three horses from nine stud farms from South-Western Poland were studied.
A. Zak   +7 more
doaj   +1 more source

Evaluation of renal perfusion in hyperthyroid cats before and after radioiodine treatment [PDF]

open access: yes, 2017
Background: Hyperthyroidism and chronic kidney disease (CKD) are common in elderly cats. Consequently, both diseases often occur concurrently. Furthermore, renal function is affected by thyroid status. Because changes in renal perfusion play an important
Adams   +34 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Dynamic mortality prediction in critically Ill children during interhospital transports to PICUs using explainable AI

open access: yesnpj Digital Medicine
Critically ill children who require inter-hospital transfers to paediatric intensive care units are sicker than other admissions and have higher mortality rates. Current transport practice primarily relies on early clinical assessments within the initial
Zhiqiang Huo   +8 more
doaj   +1 more source

4090 Dysregulation of Skeletal Muscle Mitochondrial Function following Critical Illness: a Translational Approach

open access: yesJournal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: The objective of the study was to determine whether CLP altered genes associated with mitochondrial function in the diaphragm. METHODS/STUDY POPULATION: A rodent cecal-ligation and puncture (CLP) model used to mimic sepsis-induced ...
Luther Gill, Liz Simon, Patricia Molina
doaj   +1 more source

Physical and Behavioral Measures that Predict Cats' Socialization in an Animal Shelter Environment during a Three-Day Period [PDF]

open access: yes, 2013
Information from surveys completed by the cats' caregivers provided a score for the level of socialization of cats. We examined the effectiveness of structured assessments and measures in their ability to distinguish More and Less Socialized cats in a ...
Katherine Miller   +2 more
core  

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