Results 91 to 100 of about 543,048 (284)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Raman spectroscopy and electronic microscopy structural studies of Caucasian and Afro human hair

open access: yesHeliyon, 2019
Human hair fibre is subjected to various structural modifications due to the application of chemicals such as dyes, shampoos and bleaches and/or physical procedures such as heating, and often more than one procedure is performed on the same hair.
Jordana Dias dos Santos   +2 more
doaj   +1 more source

Everyday racism and "my tram experience": emotion, civic performance and learning on YouTube [PDF]

open access: yes, 2012
Does the public expression and performance of shock, distress, anger, frustration and ideological disapproval of particular sorts of politics constitute a form of collective political expression from which individuals can learn about being citizens When ...
Banaji, Shakuntala
core   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Language and Identity in Historical Caucasian German

open access: yesCadernos de Linguística
Varieties of German outside the German-speaking area in Europe are often in close contact with surrounding languages and differ from Standard German with respect to various linguistic phenomena. We present a study on a diasporic variety of German spoken
Doris Stolberg, Katharina Dück
doaj   +1 more source

The Genre of “Memoir of a Map” in Linguistic Geography of the 18th Century

open access: yesИзвестия Южного федерального университета: Филологические науки, 2017
The paper is devoted to the rare genre of «memoir of a map» widespread in Great Britain in the 18th century. The authors analyze the little-known George Ellis’s book «Memoir of a Map of the Countries Comprehended Between the Black Sea and the Caspian ...
Denis I. Petrenko, Klara E. Shtain
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Assessing the Spatial Relationship Between Fixation and Foveal Specializations [PDF]

open access: yes, 2016
Increased cone photoreceptor density, an avascular zone (FAZ), and the displacement of inner retinal neurons to form a pit are distinct features of the human fovea.
Carroll, Joseph   +5 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Impact of safety-related dose reductions or discontinuations on sustained virologic response in HCV-infected patients: Results from the GUARD-C Cohort [PDF]

open access: yes, 2016
BACKGROUND: Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings.
Abbas, Zaigham   +303 more
core   +1 more source

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