Results 131 to 140 of about 23,286,860 (307)

Causal Processes and Propensities in Quantum Mechanics [PDF]

, 2004
In an influential article published in 1982, Bas Van Fraassen developed an argument against causal realism on the basis of an analysis of the Einstein-Podolsky-Rosen correlations of quantum mechanics. Several philosophers of science and experts in causal
Suárez, Mauricio
core  

Phosphatidylcholine’s influence on Dysmenorrhea: conclusive insights from Mendelian randomization analysis

Frontiers in Genetics
IntroductionThis study aimed to investigate the causal relationship between phosphatidylcholine (PC) levels and dysmenorrhea using Mendelian randomization (MR) analysis.MethodsWe conducted a two-sample MR analysis using GWAS data on PC levels and ...
Yuzheng Li, Shiyao Zhou, Yuchen Huang, Qiuhao Yu, Qibiao Wu, Qibiao Wu, Qibiao Wu, Qibiao Wu   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Deep Learning-Enhanced Ocean Acoustic Tomography: A Latent Feature Fusion Framework for Hydrographic Inversion with Source Characteristic Embedding

Information
Ocean Acoustic Tomography (OAT) is an important marine remote sensing technique used for inverting large-scale ocean environmental parameters, but traditional methods face challenges in computational complexity and environmental interference.
Jiawen Zhou, Zikang Chen, Yongxin Zhu, Xiaoying Zheng   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Causal Geometry and Irreversibility in Human Cognition and AI Alignment

This project presents an initial conceptual framework that applies causal and geometric structures inspired by relativity theory to human cognition and AI alignment.
Causal Geometry Research
core   +1 more source

Causality-driven localization method for improving ensemble-based Kalman filters in strongly coupled data assimilation system

Frontiers in Marine Science
Strongly coupled data assimilation (SCDA) is a critical tool for improving Earth system predictions by directly integrating observational data into coupled numerical models that simulate interactions among atmospheric, oceanic, and terrestrial components.
Tian'ao Wang, Xuan Wang, Lige Cao, Wei Li, Guijun Han   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Causal inference [PDF]

In this presentation, I provide a brief overview of quasiexperimental methods of estimating causal impacts using Stata: panel data, matching and reweighting, instrumental variables, and regression discontinuity designs, emphasizing practical ...
Austin Nichols
core