Results 111 to 120 of about 23,286,860 (307)

Causal relationship between Alzheimer’s disease and prostate cancer: a bidirectional Mendelian randomization analysis

open access: yesFrontiers in Endocrinology
BackgroundPrevious observational researchers have found an inverse bidirectional link between Alzheimer’s disease (AD) and prostate cancer (PCa); yet, the causative nature of this link remains unclear.
Rongkang Li   +9 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Causal Graphs for EPR Experiments [PDF]

open access: yes, 2013
We examine possible causal structures of experiments with entangled quantum objects. Previously, these structures have been obscured (i) by assuming a misleading probabilistic analysis of quantum non locality as 'Outcome Dependence or Parameter ...
Näger, Paul M   +2 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Hybrid Approach to Causality Analysis

open access: yes, 2015
In component-based safety-critical systems, when a system safety property is violated, it is necessary to analyze which components are the cause. Given a system execution trace that exhibits component faults leading to a property violation, our causality analysis formalizes a notion of counterfactual reasoning ("what would the system behavior be if a ...
Shaohui Wang   +4 more
openaire   +2 more sources

Implementing Causal Inference in Ecology Through the Structural Causal Model (SCM) Framework

open access: yes, 2022
Ecologists are often interested in understanding causal relationships from ecological data. However, developed methods for causal inference, particularly for observational-based studies are often not taught or applied in ecology.
Arif, Suchinta
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Causal Parameters and Policy Analysis in Economcs: A Twentieth Century Retrospective [PDF]

open access: yes
The major contributions of twentieth century econometrics to knowledge were the definition of causal parameters when agents are constrained by resources and markets and causes are interrelated, the analysis of what is required to recover causal ...
James L. Heckman
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An EG-Tree Model Incorporating Spatial Heterogeneity for Analyzing Multifactorial Coupling Effects on Carbon Emissions Across Industries and Regions in China

open access: yesAtmosphere
With the proposal of the dual carbon goals, it is of great significance to identify the causes of carbon emissions and reduce carbon emissions directly.
Jinrui Zang   +4 more
doaj   +1 more source

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