Results 141 to 150 of about 560,868 (267)

Corrigendum: Genetic liability for diet-derived circulating antioxidants, oxidative stress, and risk of osteoarthritis: a Mendelian randomization study

Frontiers in Nutrition
Yidan Tang, Yidan Tang, Xiaolin Xu, Xiaolin Xu, Shuangyi Zhang, Shuangyi Zhang, Weishuang Kong, Weiyi Zhang, Weiyi Zhang, Tao Zhu, Tao Zhu   +10 more
doaj   +1 more source

Investigating the Causal Effect of Potential Therapeutic Agents for Colorectal Cancer Prevention: A Mendelian Randomization Analysis. [PDF]

Cancer Epidemiol Biomarkers Prev
Fryer E, Bishop DT, Campbell PT, Chan AT, Le Marchand L, Li CI, Moreno V, Gunter MJ, Phipps AI, Grant RC, Schmit SL, Martin RM, Yarmolinsky J, Haycock P.   +13 more
europepmc   +1 more source

Causal Effect Identification and Inference with Endogenous Exposures and a Light-tailed Error [PDF]

Ruoyu Wang, Wang Miao
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Assessment of the causal effect of lifestyle factors on postoperative infections based on Mendelian randomization. [PDF]

Medicine (Baltimore)
Fu WJ, Ni XX, Yang H, Lian W, Xu F.
europepmc   +1 more source

Insights into different results from different causal contrasts in the presence of effect-measure modification

, 2006
Til Stürmer‎, Kenneth J. Rothman, Robert J. Glynn   +2 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

A complier average causal effect analysis of the Stimulant Reduction Intervention using dosed exercise study

, 2018
Thomas Carmody, Tracy L. Greer, Robrina Walker, Chad D. Rethorst, Madhukar H. Trivedi   +4 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Causal Impact of Immune Phenotypes on Herpes Zoster and Postherpetic Neuralgia: Insights from Mendelian Randomization Analysis

Clinical, Cosmetic and Investigational Dermatology
Zhangren Yan,1 Dandan Shen,1 Xiaoqian Qiu,2 Bohua Ai,2 Chenxi Xiong2 1Department of Traditional Chinese Medicine Surgery, Hospital of Traditional Jiangxi University of Chinese Medicine, Nanchang, 330006, People’s Republic of China; 2Graduate School ...
Yan Z, Shen D, Qiu X, Ai B, Xiong C
doaj