Results 71 to 80 of about 560,868 (267)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Michotte’s research on perceptual impressions of causality: a registered replication study
Royal Society Open ScienceMichotte (Michotte A, 1946 La perception de la causalité. Louvain: Études de Psychologie. Michotte A, 1954 La perception de la causalité, 2nd éd. Louvain: Études de Psychologie. Michotte A, 1963 The perception of causality. (Transl. by TR Miles, E Miles).
Peter White
doaj +1 more source
Causal Effect of Chondroitin, Glucosamine, Vitamin, and Mineral Intake on Kidney Function: A Mendelian Randomization Study [PDF]
, 2023 Jeong-Min Cho +15 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Unraveling drought propagation dynamics using causal inference from time series
Environmental Research LettersDrought is a pervasive natural hazard that propagates through the hydrologic cycle, leading to water deficiencies across key hydroclimatic variables such as precipitation, streamflow, and soil moisture.
Min Pang, Shuai Yang
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Efficient and Globally Robust Causal Excursion Effect Estimation [PDF]
, 2023 Zhaoxi Cheng, Lauren Bell, Tianchen Qian
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in MicrobiologyBackgroundPrevious studies have identified a clinical association between gut microbiota and Obstructive sleep apnea (OSA), but the potential causal relationship between the two has not been determined.
Liangfeng Liu +8 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source