Results 91 to 100 of about 687,701 (312)
How contrast situations affect the assignment of causality in symmetric physical settings
Frontiers in Psychology, 2015 In determining the prime cause of a physical event, people often weight one of two entities in a symmetric physical relation as more important for bringing about the causal effect than the other. In a broad survey (Bender and Beller, 2011), we documented
Sieghard eBeller, Andrea eBender
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Association of coffee intake with bone mineral density: a Mendelian randomization study
Frontiers in EndocrinologyBackgroundIn observational studies, the relationship between coffee intake and bone mineral density (BMD) is contradictory. However, residual confounding tends to bias the results of these studies. Therefore, we used a two-sample Mendelian randomization (
Yang Ye +6 more
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, 2000 For the proceedings of the conference, "Time's Arrows, Quantum Measurements and Superluminal Behavior," Naples, Italy, October 2000. To be published by the Italian CNR.
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Causal Effects for a Causal Loglinear Model
, 2015 The analysis of the causality is important in many fields of research. I propose a causal theory to obtain the causal effects in a causal loglinear model. It calculates them using the odds ratio and Pearl's causal theory. The effects are calculated distinguishing between a simple mediation model (model without the multiplicative interaction effect) and
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Optimizing Experimental Design for Causal Effect Estimation with Partial Measurements
7485Instrumental variable regression quantifies causal effects between a possibly confounded treatment variable X2 and a response variable X3 by leveraging an instrument X1.
Mareis, Leopold
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Frontiers in NeurologyBackgroundThe observational studies investigated the impact of migraine on Alzheimer’s Disease (AD). However, these findings were limited by confounding factors and reverse causation, leading to contradictory results.MethodsWe utilized Univariable ...
Chengfeng Xu +3 more
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