Results 21 to 30 of about 64,095 (292)

Causal mediation analysis with a latent mediator [PDF]

open access: yesBiometrical Journal, 2015
Health researchers are often interested in assessing the direct effect of a treatment or exposure on an outcome variable, as well as its indirect (or mediation) effect through an intermediate variable (or mediator). For an outcome following a nonlinear model, the mediation formula may be used to estimate causally interpretable mediation effects.
Albert, Jeffrey M.   +2 more
openaire   +3 more sources

Causal Mediation Analysis with Hidden Confounders [PDF]

open access: yesProceedings of the Fifteenth ACM International Conference on Web Search and Data Mining, 2022
An important problem in causal inference is to break down the total effect of a treatment on an outcome into different causal pathways and to quantify the causal effect in each pathway. For instance, in causal fairness, the total effect of being a male employee (i.e., treatment) constitutes its direct effect on annual income (i.e., outcome) and the ...
Lu Cheng 0001   +2 more
openaire   +2 more sources

Clarifying causal mediation analysis: Effect identification via three assumptions and five potential outcomes

open access: yesJournal of Causal Inference, 2022
Causal mediation analysis is complicated with multiple effect definitions that require different sets of assumptions for identification. This article provides a systematic explanation of such assumptions.
Nguyen Trang Quynh   +3 more
doaj   +1 more source

Causal mediation analysis with multiple causally non-ordered mediators [PDF]

open access: yesStatistical Methods in Medical Research, 2015
In many health studies, researchers are interested in estimating the treatment effects on the outcome around and through an intermediate variable. Such causal mediation analyses aim to understand the mechanisms that explain the treatment effect. Although multiple mediators are often involved in real studies, most of the literature considered mediation ...
Taguri, Masataka   +2 more
openaire   +4 more sources

Semiparametric Estimation for Causal Mediation Analysis with Multiple Causally Ordered Mediators [PDF]

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 2021
AbstractCausal mediation analysis concerns the pathways through which a treatment affects an outcome. While most of the mediation literature focuses on settings with a single mediator, a flourishing line of research has examined settings involving multiple mediators, under which path-specific effects (PSEs) are often of interest. We consider estimation
openaire   +3 more sources

Causal Mediation Analysis for Stochastic Interventions [PDF]

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 2020
SummaryMediation analysis in causal inference has traditionally focused on binary exposures and deterministic interventions, and a decomposition of the average treatment effect in terms of direct and indirect effects. We present an analogous decomposition of the population intervention effect, defined through stochastic interventions on the exposure ...
Díaz, Iván, Hejazi, Nima
openaire   +2 more sources

Investigating potential mediator between statin and coronary artery calcification. [PDF]

open access: yesPLoS ONE, 2018
Statins are mainstay anti-lipidaemic treatments for preventing cardiovascular diseases but also known to increase coronary artery calcification (CAC). However, underlying relationship between statin and CAC is still unclear.
Donghun Lee   +3 more
doaj   +1 more source

BayesGmed: An R-package for Bayesian causal mediation analysis.

open access: yesPLoS ONE, 2023
BackgroundThe past decade has seen an explosion of research in causal mediation analysis. However, most analytic tools developed so far rely on frequentist methods which may not be robust in the case of small sample sizes.
Belay B Yimer   +4 more
doaj   +1 more source

A general approach to causal mediation analysis. [PDF]

open access: yesPsychological Methods, 2010
Traditionally in the social sciences, causal mediation analysis has been formulated, understood, and implemented within the framework of linear structural equation models. We argue and demonstrate that this is problematic for 3 reasons: the lack of a general definition of causal mediation effects independent of a particular statistical model, the ...
Imai, Kosuke   +2 more
openaire   +4 more sources

Continuous‐time causal mediation analysis

open access: yesStatistics in Medicine, 2019
While causal mediation analysis has seen considerable recent development for a single measured mediator (M) and final outcome (Y), less attention has been given to repeatedly measured M and Y. Previous methods have typically involved discrete‐time models that limit inference to the particular measurement times used and do not recognize the continuous ...
Jeffrey M. Albert   +4 more
openaire   +4 more sources

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