Results 121 to 130 of about 1,644,838 (299)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Causal Relationship of Occupational Stress among University Employees

open access: yesIranian Journal of Public Health, 2015
Background: Occupational stress is a psychosocial dimension of occupational health concept on social determinants of health, especially, job & environmental condition.
Chonticha KAEWANUCHIT   +2 more
doaj  

Bitcoin: a Ponzi scheme or an emerging inflation-fighting asset?

open access: yesTechnological and Economic Development of Economy
Under the dual impact of the COVID-19 pandemic and the Russian-Ukrainian conflict, the excessive stimulation of monetary policy continuously pushes up global inflation (INF). Therefore, this article explores whether Bitcoin can serve as a safe haven for
Fangying Liu   +3 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

The causal relationship between 41 inflammatory cytokines and hypothyroidism: bidirectional two-sample Mendelian randomization study

open access: yesFrontiers in Endocrinology
ObjectiveInvestigating the association between inflammatory cytokines and hypothyroidism remains challenging due to limitations in traditional observational studies.
Rui Lai   +6 more
doaj   +1 more source

New Estimates on the Effect of Parental Separation on Child Health [PDF]

open access: yes
This study examines the causal link between parental non-marital relationship dissolution and the health status of young children. Using a representative sample of children all born out of wedlock drawn from the Fragile Families and Child Wellbeing Study,
Frank Heiland, Shirley H. Liu
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Causal Effects of Gut Microbiome on Tinnitus: A Mendelian Randomization Study

open access: yesJournal of Multidisciplinary Healthcare
Qiang Zeng,1 Wei Xie,2 Huaqian Dong,2 Xing Liu,1 Shuai Shao,1 Li Chen,1 Wenwen Zhang1 1School of Nursing, Guizhou University of Traditional Chinese Medicine, Guiyang, 550002, People’s Republic of China; 2Department of Nursing, the First Affiliated ...
Zeng Q   +6 more
doaj  

Causal relationship between hypothyroidism and ulcerative colitis: a bidirectional Mendelian randomization study

open access: yesBMC Gastroenterology
Objective Ulcerative colitis (UC) and Hashimoto’s thyroiditis frequently cooccur in patients with multiple autoimmune conditions, but the specific association between UC and hypothyroidism is unknown.
Yumeng Yang   +3 more
doaj   +1 more source

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