Results 231 to 240 of about 6,601,325 (263)

To unveil the causal relationship between immunophenotypes and colorectal cancer using two-sample bidirectional Mendelian randomization and mediation analyses. [PDF]

Medicine (Baltimore)
Zhang Y, Fei B, Fang X, Tian S.
europepmc   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Causal Relationship Between Methotrexate and Chronic Obstructive Pulmonary Disease: A Study Based on Network Toxicology and Mendelian Randomization. [PDF]

Int J Chron Obstruct Pulmon Dis
Xiang YX, Zou FS, Shi MF, Xu Q.
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Testing the causal relationship between interpersonal closeness and inter-brain synchrony. [PDF]

Sci Rep
Fornari L, Janssen TWP, Davidesco I, Krabbendam L, van Atteveldt N.   +4 more
europepmc   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Exploring the causal relationship between COPD and AKI: A bidirectional Mendelian randomization approach. [PDF]

Medicine (Baltimore)
Ma H, Zhou F, Luo Q.
europepmc   +1 more source

The causal relationship between multiple cardiovascular diseases and glioblastoma: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Lin K, Gao Y, Tian X, Jiang T.
europepmc   +1 more source

Causal relationship between gut microbiota and rheumatoid arthritis: A bidirectional 2-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Zhang S, Li Y, Cheng H, Gao Y, Zhao H, Ren W, Mei W.   +6 more
europepmc   +1 more source

Causal relationship between GM, immune cells and esophageal adenocarcinoma: a mediation analysis based on MR. [PDF]

J Cardiothorac Surg
He W, Gao M, Ren Q, Wang M, Zhou S, Liu Q, Chu K, Qin Y, Fan Y, Zou H, Cui Y, Shu Y, Wang X.   +12 more
europepmc   +1 more source