Results 41 to 50 of about 385,289 (314)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Three-layered semantic framework for public health intelligence

open access: yesJournal of Biomedical Semantics
Background Disease surveillance systems play a crucial role in monitoring and preventing infectious diseases. However, the current landscape, primarily focused on fragmented health data, poses challenges to contextual understanding and decision-making ...
Sathvik Guru Rao   +8 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Causality-aided Recommendation Systems

open access: yes, 2022
Causality-aided Recommendation ...
B Duong (14627612)   +2 more
core  

Causal Loops and the Independence of Causal Facts [PDF]

open access: yesPhilosophy of Science, 2001
According to Hugh Mellor in Real Time II (1998, Ch. 12), assuming the logical independence of causal facts and the ‘law of large numbers’, causal loops are impossible because if they were possible they would produce inconsistent sets of frequencies.
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Causality and Causal Models: A Conceptual Perspective*

open access: yesInternational Statistical Review, 2006
SummaryThis paper aims at displaying a synthetic view of the historical development and the current research concerning causal relationships, starting from the Aristotelian doctrine of causes, following with the main philosophical streams until the middle of the twentieth century, and commenting on the present intensive research work in the statistical
openaire   +2 more sources

Causal Networks or Causal Islands? The Representation of Mechanisms and the Transitivity of Causal Judgment [PDF]

open access: yesCognitive Science, 2015
AbstractKnowledge of mechanisms is critical for causal reasoning. We contrasted two possible organizations of causal knowledge—an interconnected causalnetwork, where events are causally connected without any boundaries delineating discrete mechanisms; or a set of disparate mechanisms—causalislands—such that events in different mechanisms are not ...
Samuel G. B. Johnson, Woo-kyoung Ahn
openaire   +2 more sources

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