Results 41 to 50 of about 899,059 (298)
, 2013 In biological systems, closure refers to a holistic feature such that their constitutive processes, operations and transformations (1) depend on each other for their production and maintenance and (2) collectively contribute to determine the conditions at which the whole organization can exist.
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Three-layered semantic framework for public health intelligence
Journal of Biomedical SemanticsBackground Disease surveillance systems play a crucial role in monitoring and preventing infectious diseases. However, the current landscape, primarily focused on fragmented health data, poses challenges to contextual understanding and decision-making ...
Sathvik Guru Rao +8 more
doaj +1 more source
Strong Cosmic Censorship and Causality Violation
, 1997 We investigate the instability of the Cauchy horizon caused by causality violation in the compact vacuum universe with the topology $B\times {\bf S}^{1}\times {\bf R}$, which Moncrief and Isenberg considered.
A. Ishibashi +24 more
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The American Statistician, 2019 Although no universally accepted definition of causality exists, in practice one is often faced with the question of statistically assessing causal relationships in different settings. We present a uniform general approach to causality problems derived from the axiomatic foundations of the Bayesian statistical framework.
Pierre Baldi, Babak Shahbaba
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Information causality from an entropic and a probabilistic perspective
, 2011 The information causality principle is a generalisation of the no-signalling principle which implies some of the known restrictions on quantum correlations.
Al-Safi, Sabri W., Short, Anthony J.
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
, 2010 The importance for cosmology of the recently introduced ELKOs requires our deepest understanding of them and of all of their fundamental properties.
Fabbri, Luca
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source