Results 61 to 70 of about 473,721 (315)

Cathepsins and cancer risk: a Mendelian randomization study

open access: yesFrontiers in Endocrinology
BackgroundPrevious observational epidemiological studies reported an association between cathepsins and cancer, however, a causal relationship is uncertain.
Tingting Deng   +10 more
doaj   +1 more source

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida   +11 more
wiley   +1 more source

COSMIC EVIDENCE AND NATURAL-SCIENCE THEORIES [PDF]

open access: yesHum, 2008
Aspiration for discovering one necessary creature, who establishes visible and changeable cosmos, has existed in the early period of philosophical thinking. In philosophical tradition the most acknowledged way of determining existence of such creature
Mate Buntić
doaj  

Quantile treatment effect estimation with dimension reduction

open access: yesStatistical Theory and Related Fields, 2020
Quantile treatment effects can be important causal estimands in evaluation of biomedical treatments or interventions for health outcomes such as medical cost and utilisation.
Ying Zhang   +3 more
doaj   +1 more source

Causal Networks or Causal Islands? The Representation of Mechanisms and the Transitivity of Causal Judgment [PDF]

open access: yesCognitive Science, 2015
AbstractKnowledge of mechanisms is critical for causal reasoning. We contrasted two possible organizations of causal knowledge—an interconnected causalnetwork, where events are causally connected without any boundaries delineating discrete mechanisms; or a set of disparate mechanisms—causalislands—such that events in different mechanisms are not ...
Samuel G. B. Johnson, Woo-kyoung Ahn
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A study on large-scale disease causality discovery from biomedical literature

open access: yesBMC Medical Informatics and Decision Making
Background Biomedical semantic relationship extraction could reveal important biomedical entities and the semantic relationships between them, providing a crucial foundation for the biomedical knowledge discovery, clinical decision making and other ...
Shirui Yu   +4 more
doaj   +1 more source

Causality-based Testing of Autonomous Driving Systems

open access: yes, 2023
 This is the replication package for " Causality-based Testing of Autonomous Driving Systems ". 
CART (14488355)
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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