Results 81 to 90 of about 385,289 (314)

Causal Set Theory is (Strongly) Causal

open access: yesFoundations of Physics
Abstract Causal Set Theory (CST) is a promising approach to fundamental physics that seems to treat causation as a basic posit. But in exactly what sense is CST causal? We argue that if the growth dynamics is interpreted as a physical process, then CST employs relations of actual causation between causal set elements, whereby elements bring ...
Baron, Sam, Le Bihan, Baptiste
openaire   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

A Panel Data Approach for Income-Health Causality [PDF]

open access: yes
This study provides evidence on income-health causality by employing a large micro panel data set with a VAR representation. The findings verify that dominant type of causality is bidirectional which cast doubt on the performance OLS estimates in the ...
I. Hakan Yetkiner, Erkan Erdil
core  

Association between hypothyroidism and obstructive sleep apnea: a bidirectional Mendelian randomization study combined with the geo database

open access: yesFrontiers in Neurology
BackgroundThe causal relationship between hypothyroidism and obstructive sleep apnea (OSA) remains controversial. Therefore, our research used a bidirectional Mendelian randomization (MR) method in an attempt to determine the causal relationship between ...
Mingyu Zhao   +6 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Carbon Emissions and Economic Growth: Homogeneous Causality in Heterogeneous Panels [PDF]

open access: yes
This paper introduces the concept of homogeneous non-causality in heterogeneous panels. This concept is used to examine a panel of data for evidence of a causal relationship between GDP and carbon emissions. The technique is compared to the standard test
David J. Maddison, Katrin Rehdanz
core  

Gazzâlî’nin Mûcizeye Yaklaşımının Tehâfütü’l-Felâsife Bağlamında Kuantum Kuramı Açısından Değerlendirilmesi

open access: yesKader
Klasik fizik anlayışını değiştiren kuantum kuramı, bilimsel sahada ilk defa ortaya çıkan indeterminizm olması bakımından felsefe ve teoloji alanlarında da büyük etkiler meydana getirmiştir.
Ahmet Çelik, Ayşe Kocabaş
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Post-traumatic Appendicitis in Pediatric Patients: A Report of Three Cases

open access: yesIatreia
Introduction: Acute appendicitis is the most common surgical emergency in pediatric patients. However, the occurrence of this condition following abdominal trauma is rare, representing only 0.3% of all causes, with few case reports in the medical ...
Alvarez-Carrascal, Juan Manuel   +1 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

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