Results 91 to 100 of about 473,721 (315)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Post-traumatic Appendicitis in Pediatric Patients: A Report of Three Cases
IatreiaIntroduction: Acute appendicitis is the most common surgical emergency in pediatric patients. However, the occurrence of this condition following abdominal trauma is rare, representing only 0.3% of all causes, with few case reports in the medical ...
Alvarez-Carrascal, Juan Manuel +1 more
doaj +1 more source
Causal Set Theory is (Strongly) Causal
Foundations of PhysicsAbstract Causal Set Theory (CST) is a promising approach to fundamental physics that seems to treat causation as a basic posit. But in exactly what sense is CST causal? We argue that if the growth dynamics is interpreted as a physical process, then CST employs relations of actual causation between causal set elements, whereby elements bring ...
Baron, Sam, Le Bihan, Baptiste
openaire +1 more source
The Relation of Different Concepts of Causality in Econometrics [PDF]
Granger and Sims non-causality (GSNC) are compared to non-causality based on concepts popular in the microeconometrics and programme evaluation literature (potential outcome non-causality, PONC).
Michael Lechner
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Vascular normalization confers an endothelial immune suppressive gene expression profile
Molecular Oncology, EarlyView.We compare the immunoregulatory gene expression profiles of healthy endothelial cells or endothelial cells from tumors having a normalized endothelium (low leakage) with that of wild‐type tumors (high leakage) and observe that the wild‐type tumor endothelium exhibits immunostimulatory properties.
Liqun He, Michael Welsh
wiley +1 more source
Machine Learning: Science and TechnologyRecent advancements in large foundation models have revealed impressive capabilities in mastering complex chemical language representations. These models undergo a task-agnostic learning phase, characterized by pre-training on extensive unlabeled corpora
Eduardo Soares +7 more
doaj +1 more source
Kointegrasi dan kausalitas pasar saham Big 5 ASEAN: Tax Amnesty gelombang I
Journal of Business & Banking, 2017 The first batch of Tax Amnesty policy in Indonesia can affect the economy in other countries because of international cooperation, especially in ASEAN. This study tried to see the cointegration and the causality between stock market indices in the Big 5 ...
Loe Irene Kusuma +2 more
doaj +1 more source
Causality between Openness and Indigenous Factors among World Economies [PDF]
The paper studies the causality relationship between economic openness and indigenous factors. The construction of the Openness Index and the Indigenous Index provides a measure on the extent of openness and indigenous development among world economies ...
Li, Kui-Wai, Zhou, X.
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source