Results 71 to 80 of about 899,059 (298)
Causal holographic information [PDF]
Journal of High Energy Physics, 2012 We propose a measure of holographic information based on a causal wedge construction. The motivation behind this comes from an attempt to understand how boundary field theories can holographically reconstruct spacetime. We argue that given the knowledge of the reduced density matrix in a spatial region of the boundary, one should be able to reconstruct
Hubeny, Veronika E., Rangamani, Mukund
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FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Frontiers in Psychology, 2013 AbstractRasch’s unidimensional models for measurement show how to connect object measures (e.g., reader abilities), measurement mechanisms (e.g., machine-generated cloze reading items), and observational outcomes (e.g., counts correct on reading instruments).
Stenner, A. Jackson +3 more
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
SSRN Electronic Journal, 2008 Summary This paper presents the econometric approach to causal modelling. It is motivated by policy problems. New causal parameters are defined and identified to address specific policy problems. Economists embrace a scientific approach to causality and model the preferences and choices of agents to infer subjective (agent) evaluations as well as ...
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Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
General Relativity from Causality
, 2017 We study large families of theories of interacting spin 2 particles from the point of view of causality. Although it is often stated that there is a unique Lorentz invariant effective theory of massless spin 2, namely general relativity, other theories ...
Hertzberg, Mark P., Sandora, McCullen
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Causality Without Causal Models
Electronic Proceedings in Theoretical Computer ScienceIn Proceedings TARK 2025, arXiv:2511 ...
Halpern, Joseph Y., Pass, Rafael
openaire +2 more sources