Results 51 to 60 of about 451,043 (309)
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Three-layered semantic framework for public health intelligence
Journal of Biomedical SemanticsBackground Disease surveillance systems play a crucial role in monitoring and preventing infectious diseases. However, the current landscape, primarily focused on fragmented health data, poses challenges to contextual understanding and decision-making ...
Sathvik Guru Rao +8 more
doaj +1 more source
Sociological Methods & Research, 2019 Does X affect Y? Answering this question is particularly difficult if reverse causality is looming. Many social scientists turn to panel data to address such questions of causal ordering.
Lars Leszczensky, Tobias Wolbring
semanticscholar +1 more source
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
Causal Networks or Causal Islands? The Representation of Mechanisms and the Transitivity of Causal Judgment [PDF]
Cognitive Science, 2015 AbstractKnowledge of mechanisms is critical for causal reasoning. We contrasted two possible organizations of causal knowledge—an interconnected causalnetwork, where events are causally connected without any boundaries delineating discrete mechanisms; or a set of disparate mechanisms—causalislands—such that events in different mechanisms are not ...
Samuel G. B. Johnson, Woo-kyoung Ahn
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
From correlation to causality: the case of Subdoligranulum
Gut microbes, 2020 Gut microbes are considered as major factors contributing to human health. Nowadays, the vast majority of the data available in the literature are mostly exhibiting negative or positive correlations between specific bacteria and metabolic parameters ...
M. Van Hul +9 more
semanticscholar +1 more source
Causality and Causal Models: A Conceptual Perspective*
International Statistical Review, 2006 SummaryThis paper aims at displaying a synthetic view of the historical development and the current research concerning causal relationships, starting from the Aristotelian doctrine of causes, following with the main philosophical streams until the middle of the twentieth century, and commenting on the present intensive research work in the statistical
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko +19 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan +15 more
wiley +1 more source