Results 51 to 60 of about 899,059 (298)

Plasma fatty acids and attention deficit hyperactivity disorder: a Mendelian randomization investigation

Frontiers in Psychiatry
BackgroundAttention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood, and pathogenesis is not fully understood.
Kangning Zhou, Qiang Zhang, Zhenhua Yuan, Yurou Yan, Qian Zhao, Junhong Wang   +5 more
doaj   +1 more source

Time Series Analysis of Causal Relationship among Sectoral Labor Productivity in Turkey

Turkish Journal of Agriculture: Food Science and Technology, 2017
In this paper, we investigate the causal relationship in terms of labor productivity among GDP and its constituent three main sectors, e.g. agricultural, industrial and services sectors, in Turkey for the period of 1988-2015.
Cevher Özden, Filiz Yetiz
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Boundary Causality vs Hyperbolicity for Spherical Black Holes in Gauss-Bonnet

, 2016
We explore the constraints boundary causality places on the allowable Gauss-Bonnet gravitational couplings in asymptotically AdS spaces, specifically considering spherical black hole solutions.
Andrade, Tomas, Caceres, Elena, Keeler, Cynthia   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A study on large-scale disease causality discovery from biomedical literature

BMC Medical Informatics and Decision Making
Background Biomedical semantic relationship extraction could reveal important biomedical entities and the semantic relationships between them, providing a crucial foundation for the biomedical knowledge discovery, clinical decision making and other ...
Shirui Yu, Peng Dong, Junlian Li, Xiaoli Tang, Xiaoying Li   +4 more
doaj   +1 more source

Cathepsins and cancer risk: a Mendelian randomization study

Frontiers in Endocrinology
BackgroundPrevious observational epidemiological studies reported an association between cathepsins and cancer, however, a causal relationship is uncertain.
Tingting Deng, Xixue Lu, Xuemin Jia, Jinxin Du, Lijuan Wang, Lijuan Wang, Baorui Cao, Meina Yang, Meina Yang, Ying Yin, Fanjie Liu   +10 more
doaj   +1 more source

Causal imprinting in causal structure learning [PDF]

Cognitive Psychology, 2012
Suppose one observes a correlation between two events, B and C, and infers that B causes C. Later one discovers that event A explains away the correlation between B and C. Normatively, one should now dismiss or weaken the belief that B causes C. Nonetheless, participants in the current study who observed a positive contingency between B and C followed ...
Eric G, Taylor, Woo-Kyoung, Ahn
openaire   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Experimental scenarios in accounting research: Highlights in methodological development

Revista Contabilidade & Finanças, 2023
The main objective of this article is to guide the researcher, through the exposition of highlights and examples from previous literature, in the building of an experimental scenario for the investigation of his research question.
Myrna Modolon Lima
doaj   +2 more sources