Results 61 to 70 of about 2,417,970 (339)

Assessing the quality of medical death certification: a case study of concordance between national statistics and results from a medical record review in a regional hospital in the Philippines

open access: yesPopulation Health Metrics, 2018
Background Medical certificates of cause of death (MCCOD) issued by hospital physicians are a key input to vital registration systems. Deaths certified by hospital physicians have been implicitly considered to be of high quality, but recent evidence ...
Marilla Lucero   +7 more
doaj   +1 more source

Neonatal cause-of-death estimates for the early and late neonatal periods for 194 countries: 2000–2013

open access: yesBulletin of the World Health Organization, 2014
Objective To estimate cause-of-death distributions in the early (0–6 days of age) and late (7–27 days of age) neonatal periods, for 194 countries between 2000 and 2013. Methods For 65 countries with high-quality vital registration, we used each country’s
S. Oza   +4 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Mortality risk and causes of death in patients with non-cystic fibrosis bronchiectasis

open access: yesRespiratory Research, 2019
Background All-cause mortality risk and causes of death in bronchiectasis patients have not been fully investigated. The aim of this study was to compare the mortality risk and causes of death between individuals with bronchiectasis and those without ...
Sooim Sin   +12 more
doaj   +1 more source

Cause of death for patients with breast cancer: discordance between death certificates and medical files, and impact on survival estimates

open access: yesArchives of Public Health, 2021
Background Registration and coding of cause of death is prone to error since determining the exact underlying condition leading directly to death is challenging.
Hava Izci   +16 more
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Intracranial injuries in the autopsy material of the Department of Forensic Medicine of the Medical University of Lodz with analysis of anatomical lesions caused by traumatic brain injuries

open access: yesTranslational Research in Anatomy
Background: In 2022, 408 autopsies were performed in the Department of Forensic Medicine of the Lodz Medical University, of which as many as 82 concerned deaths with intracranial injuries, which represents about 20 % of all performed autopsies.
Anna Smędra   +4 more
doaj   +1 more source

Fatality from COVID-19 does not affect palliative care duration among patients with advanced cancer: a retrospective cohort study [PDF]

open access: yesEinstein (São Paulo)
Objective: This study aimed at investigating the extent to which COVID-19-induced fatalities affect the duration of palliative care among patients with advanced cancer.
Rafael Tavares Jomar   +5 more
doaj   +1 more source

Forensic Analysis of 52 Corpses Found in Wells [PDF]

open access: yesFayixue Zazhi, 2019
Objective To explore the forensic pathological characteristics of corpses in wells, and to summarize the differences in corpses between homicide and suicide, so as to provide references for forensic analysis of such cases.
CUI Wan-chao, ZHANG Wen-juan
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

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