Results 61 to 70 of about 2,417,970 (339)
Background Medical certificates of cause of death (MCCOD) issued by hospital physicians are a key input to vital registration systems. Deaths certified by hospital physicians have been implicitly considered to be of high quality, but recent evidence ...
Marilla Lucero+7 more
doaj +1 more source
Objective To estimate cause-of-death distributions in the early (0–6 days of age) and late (7–27 days of age) neonatal periods, for 194 countries between 2000 and 2013. Methods For 65 countries with high-quality vital registration, we used each country’s
S. Oza+4 more
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Mortality risk and causes of death in patients with non-cystic fibrosis bronchiectasis
Background All-cause mortality risk and causes of death in bronchiectasis patients have not been fully investigated. The aim of this study was to compare the mortality risk and causes of death between individuals with bronchiectasis and those without ...
Sooim Sin+12 more
doaj +1 more source
Background Registration and coding of cause of death is prone to error since determining the exact underlying condition leading directly to death is challenging.
Hava Izci+16 more
doaj +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Background: In 2022, 408 autopsies were performed in the Department of Forensic Medicine of the Lodz Medical University, of which as many as 82 concerned deaths with intracranial injuries, which represents about 20 % of all performed autopsies.
Anna Smędra+4 more
doaj +1 more source
Fatality from COVID-19 does not affect palliative care duration among patients with advanced cancer: a retrospective cohort study [PDF]
Objective: This study aimed at investigating the extent to which COVID-19-induced fatalities affect the duration of palliative care among patients with advanced cancer.
Rafael Tavares Jomar+5 more
doaj +1 more source
Forensic Analysis of 52 Corpses Found in Wells [PDF]
Objective To explore the forensic pathological characteristics of corpses in wells, and to summarize the differences in corpses between homicide and suicide, so as to provide references for forensic analysis of such cases.
CUI Wan-chao, ZHANG Wen-juan
doaj +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász+6 more
wiley +1 more source