Results 151 to 160 of about 2,926,770 (304)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Causes of death in NBA players: a competing risks analysis. [PDF]
BMJ Open Sport Exerc MedMartínez JA +5 more
europepmc +1 more source
Revisiting the mortality of France and Italy with the multiple-cause-of-death approach [PDF]
In this paper, we use the multiple cause-of-death approach to compare the mortality profiles of France and Italy in 2003. Our analysis leads to a substantial re-evaluation of the role played by certain conditions in the process leading to death ...
Aline Desesquelles +6 more
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Causes of death from community settings: insights from verbal autopsy implementation in Tanzania. [PDF]
BMJ Glob HealthLyatuu I +7 more
europepmc +1 more source
Survey of epidemiology of burns injuries lead to death since 10 years ago in Ardabil City, Iran [PDF]
Introduction: Burn injuries are a major health problem and still produce a significant morbidity and mortality in developing countries. Although there are no articles dealing with epidemiological studies of burn injuries in Ardabil city , so ...
بابایی, ارسلان +2 more
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Mortality and Causes of Death After Metabolic Bariatric Surgery in Older Patients. [PDF]
Obes SurgGerber P +4 more
europepmc +1 more source