Results 91 to 100 of about 18,681 (274)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Smooth elastic contact of cylinders by caustics: the contact length in the Brazilian disc test
Archives of Mechanics, 2013 The smooth contact of two elastic cylinders compressed against each other along a common generatrix is studied analytically and experimentally. The main objective is the quantification of the length of the contact arc. For the analytic study, the complex
S.K. Kourkoulis +2 more
doaj +1 more source
Caustics of $1/r^n$ binary gravitational lenses: from galactic haloes to exotic matter
, 2016 We investigate the caustic topologies for binary gravitational lenses made up of two objects whose gravitational potential declines as $1/r^n$. With $n1$ regime can be obtained with some violations of the energy conditions, one famous example being the ...
Bozza, V., Melchiorre, C.
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Restoring geometrical optics near caustics using sequenced metaplectic transforms
New Journal of Physics, 2020 Geometrical optics (GO) is often used to model wave propagation in weakly inhomogeneous media and quantum-particle motion in the semiclassical limit. However, GO predicts spurious singularities of the wavefield near reflection points and, more generally,
N A Lopez, I Y Dodin
doaj +1 more source
Propagation of charged particle waves in a uniform magnetic field
, 2012 This paper considers the probability density and current distributions generated by a point-like, isotropic source of monoenergetic charges embedded into a uniform magnetic field environment.
Arnulfo Gonzalez +22 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Physical Review Accelerators and Beams, 2016 Current modulations, current spikes, and current horns, are observed in a range of accelerator physics applications including strong bunch compression in Free Electron Lasers and linear colliders, trains of microbunching for terahertz radiation ...
T. K. Charles +2 more
doaj +1 more source
Esophageal Mucosal Injuries From Drugs, Radiation, and Caustic Agents [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal ResearchVarious factors can lead to esophageal mucosal injury. A thorough patient history is crucial to accurately diagnose esophageal injuries caused by drugs, radiation, and caustic agents.
Hyung Jin Bae, Younghee Choe
doaj +1 more source