CAV-2-Mediated GFP and LRRK2G2019S Expression in the Macaca fascicularis Brain. [PDF]
Front Mol Neurosci, 2020 Parkinson's disease is characterized by motor and nonmotor symptoms that gradually appear as a consequence of the selective loss of dopaminergic neurons in the substantia nigra pars compacta. Currently, no treatment can slow Parkinson's disease progression.
di Caudo C +8 more
europepmc +6 more sources
Editorial: Tropism, Mapping, Modeling, or Therapy Using Canine Adenovirus Type 2 (CAV-2) Vectors in the CNS. [PDF]
Front Mol Neurosci, 2021 Dopeso-Reyes IG +3 more
europepmc +6 more sources
Targeting Catecholaminergic Systems in Transgenic Rats With a CAV-2 Vector Harboring a Cre-Dependent DREADD Cassette. [PDF]
Front Mol Neurosci, 2020 Techniques that allow the manipulation of specific neural circuits have greatly increased in the past few years. DREADDs (Designer receptors exclusively activated by designer drugs) provide an elegant way to manipulate individual brain structures and/or neural circuits, including neuromodulatory pathways. Considerable efforts have been made to increase
Cerpa JC +5 more
europepmc +5 more sources
Targeting Reciprocally Connected Brain Regions Through CAV-2 Mediated Interventions. [PDF]
Front Mol Neurosci, 2019 An important issue in contemporary neuroscience is to identify functional principles at play within neural circuits. The reciprocity of the connections between two distinct brain areas appears as an intriguing feature of some of these circuits. This organization has been viewed as "re-entry," a process whereby two or more brain regions concurrently ...
Morceau S, Piquet R, Wolff M, Parkes SL.
europepmc +5 more sources
Frontiers in Veterinary Science, 2021 Canine adenovirus type 2 (CAdV-2) is often found in co-infections with other pathogens causing canine infectious respiratory disease (CIRD). Rapid, efficient, and convenient pathogen detection is the best approach for early confirmatory diagnosis.
Li Xiao +7 more
doaj +1 more source
A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons [PDF]
Neuron, 2018 Retrogradely transported neurotropic viruses enable genetic access to neurons based on their long-range projections and have become indispensable tools for linking neural connectivity with function. A major limitation of viral techniques is that they rely on cell-type-specific molecules for uptake and transport.
Shu-Jing, Li +3 more
openaire +2 more sources
The expression and significance of serum caveolin-1 in patients with Kawasaki disease
Chinese Journal of Physiology, 2020 We investigated the expression of caveolin-1 (Cav-1) in Kawasaki disease (KD) and analyzed its relationship with coronary artery lesions (CALs). Cav-1 participated in the progression of CAL in KD.
Feng Zhu +9 more
doaj +1 more source
Development of TaqMan Real-Time Polymerase Chain Reaction Assay for Detection of Chicken Anemia Virus in Newcastle Disease Vaccines [PDF]
Archives of Razi Institute, 2021 Exogenous chicken anemia virus (CAV) has been detected in commercial poultry vaccines in various countries of the world. The presence of unwanted CAV in vaccines not only influences the epidemiology of chicken infectious anemia disease, but may also lead
A Kaffashi +2 more
doaj +1 more source
Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
Frontiers in Immunology, 2017 Caveolins, encoded by the CAV gene family, are the main protein components of caveolae. In most tissues, caveolin-1 (Cav-1) and caveolin-2 (Cav-2) are co-expressed, and Cav-2 targeting to caveolae depends on the formation of heterooligomers with Cav-1 ...
Cecília Jacques Gonçalves de Almeida
doaj +1 more source
Cells, 2023 Caveolin-1 (Cav-1) induces cellular senescence by reducing extracellular signal-regulated kinase (ERK)1/2 phosphorylation and activating p53 via inhibition of mouse double minute 2 homolog (MDM2) and sirtuin 1 (Sirt1), promoting cell cycle arrest and ...
Seyeon Oh +4 more
doaj +1 more source