Results 251 to 260 of about 57,111 (301)
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Experimental Neurology, 2019
Dendritic and synaptic plasticity in the penumbra are important processes and are considered to be therapeutic targets of ischemic stroke. Treadmill exercise is known to be a beneficial treatment following stroke.
Qingfeng Xie +9 more
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Dendritic and synaptic plasticity in the penumbra are important processes and are considered to be therapeutic targets of ischemic stroke. Treadmill exercise is known to be a beneficial treatment following stroke.
Qingfeng Xie +9 more
semanticscholar +1 more source
Caveolins and membrane cholesterol
Biochemical Society Transactions, 2004Caveolae (small plasma membrane invaginations) and their coat proteins, caveolins, have attracted the attention of researchers in diverse fields, including cell biology, cardiovascular and cancer research. The tight association between caveolin and cholesterol governs the biochemical behaviour of caveolae and is emerging as an important characteristic ...
E, Ikonen, S, Heino, S, Lusa
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Current Opinion in Cell Biology, 1996
In the past year, we have witnessed considerable progress towards an understanding of the workings of caveolae. Highlights include the identification of new caveolin family members, the characterization of VIP21-caveolin as a cholesterol-binding oligomeric protein, and evidence for functional interactions between caveolins and heterotrimeric G proteins.
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In the past year, we have witnessed considerable progress towards an understanding of the workings of caveolae. Highlights include the identification of new caveolin family members, the characterization of VIP21-caveolin as a cholesterol-binding oligomeric protein, and evidence for functional interactions between caveolins and heterotrimeric G proteins.
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2001
Experimental protocols that allow confident assignment of signaling proteins to specific subdomains of the plasma membrane are essential for a full understanding of the complexities of signal transduction. This is especially relevant for Ras proteins, where the different membrane anchors of the Ras isoforms target them to functionally distinct ...
Parton, R. G., Hancock, J. F.
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Experimental protocols that allow confident assignment of signaling proteins to specific subdomains of the plasma membrane are essential for a full understanding of the complexities of signal transduction. This is especially relevant for Ras proteins, where the different membrane anchors of the Ras isoforms target them to functionally distinct ...
Parton, R. G., Hancock, J. F.
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1999
Abstract Caveolins are principal components of caveolae, non-clathrin coated flask-shaped invaginations of the plasma membrane which are present in many mammalian cell types but are particularly abundant in endothelial cells, smooth muscle cells, adipocytes, and fibroblasts.
Anton G Rietveld, Kai Simons
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Abstract Caveolins are principal components of caveolae, non-clathrin coated flask-shaped invaginations of the plasma membrane which are present in many mammalian cell types but are particularly abundant in endothelial cells, smooth muscle cells, adipocytes, and fibroblasts.
Anton G Rietveld, Kai Simons
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Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis
Trends in Cell Biology, 1994Caveolae, 50-100 nm invaginations that represent a subcompartment of the plasma membrane, have been known for many years, but their exact roles remain uncertain. The findings that the caveolae coat protein caveolin is a v-Src substrate and that G-protein-coupled receptors are present in caveolae have suggested a relationship between caveolae, caveolin ...
M P, Lisanti +3 more
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2012
Caveolins serve as a platform in plasma membrane associated caveolae to orchestrate various signaling molecules to effectively communicate extracellular signals into the interior of cell. All three types of caveolin, Cav-1, Cav-2 and Cav-3 are expressed throughout the cardiovascular system especially by the major cell types involved including ...
Mathivadhani, Panneerselvam +2 more
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Caveolins serve as a platform in plasma membrane associated caveolae to orchestrate various signaling molecules to effectively communicate extracellular signals into the interior of cell. All three types of caveolin, Cav-1, Cav-2 and Cav-3 are expressed throughout the cardiovascular system especially by the major cell types involved including ...
Mathivadhani, Panneerselvam +2 more
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Caveolin and Endothelial NO Signaling
2018Pulmonary vascular diseases are associated with several factors including infection, cigarette smoking, abuse of dietary suppressants and drugs, prolonged exposure to high altitude, and other causes which in part induce significant oxidative stress resulting in endothelial cell injury, apoptosis, hyperproliferation, and vaso-occlusive disease ...
Suellen D S, Oliveira +1 more
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Atherosclerosis, Caveolae and Caveolin-1
2012Atherosclerosis is a disease of the blood vessel characterized by the development of an arterial occlusion containing lipid and cellular deposits. Caveolae are 50-100 nm cell surface plasma membrane invaginations that are believed to play an important role in the regulation of cellular signaling and transport of molecules among others. These organelles
Pavlides, Stephanos +4 more
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Caveolins and Cellular Cholesterol Balance
Traffic, 2000Caveolins are major integral membrane components of caveolae. Over the last few years, evidence has accumulated for a close link between caveolin, caveolae, and the regulation of cellular cholesterol levels. However, the exact role of caveolin in this process, the intracellular trafficking routes followed by caveolin/cholesterol complexes, and the ...
Ikonen, E., Parton, R. G.
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