Results 161 to 170 of about 63,367 (249)

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

Decoding the Role of Caveolin‐1 in Morphological Diversity and Self‐Renewal of Breast Cancer Cells

Cell Proliferation, Volume 59, Issue 5, May 2026.
The silence of caveolin‐1 (Cav‐1) reproduced the morphological evolutionary behaviour of cancer cells, which is similar to the epithelial‐mesenchymal transition process. And Cav‐1 dependent morphological changes could affect cancer cell self‐renewal capacity through maintaining the morphological stability.
Shun Li, Hongyun Duan, Lu Yang, Lingyi Jiang, Haocheng Bian, Yuqin Jiang, Yixi Zhang, Wei Yan, Qin Yang, Tingting Li, Xiang Qin, Zong‐Yuan Liu, Ningwei Sun, Kai‐fu Yang, Yiyao Liu   +14 more
wiley   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Caveolin-1 is upregulated in gastric cancer and is associated with tumor progression and prognosis in patients. [PDF]

Int J Clin Exp Pathol
Jiang LJ, Lu SP, Wang Y, Shao JK, Huang BF, Wang CQ.   +5 more
europepmc   +1 more source

Caveolin 1 caveolae protein 22kDa (CAV1); caveolin 2 (CAV2) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Progression of Established Atherosclerotic Lesions Is Not Inhibited by Endothelial Knockout of Caveolin-1-Brief Report. [PDF]

Arterioscler Thromb Vasc Biol
Muñiz-Anquela R, Redondo-Angulo I, Lewis EA, Lolo FN, González-Cintado L, Toledano-Donado M, Pulgarín-Alfaro M, Del Pozo MA, Bentzon JF.   +8 more
europepmc   +1 more source

Caveolin-1 Regulates Ultrastructural Alterations of Astrocytes in Chronic Cerebral Hypoperfusion. [PDF]

Inflammation
Wu M, Zhang X, Wang D, Shu X, Chen D, Zhao Y, Lv Q, Li Y, Huang Z, Gao J, Zhu W, Wang Z, Liu X, Xie Y.   +13 more
europepmc   +1 more source

Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin–stimulated, cAMP-mediated lipolysis [PDF]

, 2018
Gross, Richard W., Kuo, Andrew, Lee, Monica Y., Sessa, William C., Yang, Kui   +4 more
core   +2 more sources

Caveolin-1 as a Marker of Endothelial Damage in Primary Antiphospholipid Syndrome Nephropathy. [PDF]

Kidney Med
Sciascia S, Radin M, Cecchi I, Barinotti A, Trevisani F, Fenoglio R, De Simone E, Roccatello D, Cassoni P, Barreca A.   +9 more
europepmc   +1 more source

Caveolin-1 modulates Notch transcriptional activity during in vitro respiratory multiciliated cell maturation. [PDF]

Sci Rep
Olivera-Gómez M, Cumplido-Laso G, Benitez DA, Barrera-Lopez JF, Del Valle-Del Pino N, Díaz-Pizarro A, Toledano-Donado M, Catala-Montoro M, Mulero-Navarro SM, Roman ÁC, Del Pozo MÁ, Carvajal-Gonzalez JM.   +11 more
europepmc   +1 more source