Results 1 to 10 of about 3,017 (109)

Unraveling the Cave: A Seventy-Year Journey into the Caveolar Network, Cellular Signaling, and Human Disease [PDF]

Cells, 2023
In the mid-1950s, a groundbreaking discovery revealed the fascinating presence of caveolae, referred to as flask-shaped invaginations of the plasma membrane, sparking renewed excitement in the field of cell biology.
Alessio D’Alessio
doaj   +2 more sources

Caveolin and oxidative stress in cardiac pathology [PDF]

Frontiers in Physiology
Caveolins interact with signaling molecules within caveolae and subcellular membranes. Dysregulation of caveolin function and protein abundance contributes to cardiac pathophysiological processes, driving the development and progression of heart disease.
Lauren Zadorozny, Lauren Zadorozny, Jiayue Du, Jiayue Du, Neil Supanekar, Karthik Annamalai, Qing Yu, Qing Yu, Meijing Wang, Meijing Wang   +9 more
doaj   +2 more sources

The importance of caveolin as a target in the prevention and treatment of diabetic cardiomyopathy [PDF]

Frontiers in Immunology, 2022
The diabetic population has been increasing in the past decades and diabetic cardiomyopathy (DCM), a pathology that is defined by the presence of cardiac remodeling and dysfunction without conventional cardiac risk factors such as hypertension and ...
Weiyi Xia, Weiyi Xia, Xia Li, Qingping Wu, Aimin Xu, Liangqing Zhang, Zhengyuan Xia, Zhengyuan Xia   +7 more
doaj   +2 more sources

Upregulation of aquaporin-2 and caveolins in rat bladder with outlet obstruction-induced detrusor overactivity [PDF]

Investigative and Clinical Urology
Purpose: Bladder outlet obstruction (BOO) leads to detrusor overactivity (DO) and structural remodeling of the bladder. However, the molecular mechanisms underlying this process remain incompletely understood.
Seong Hyeon Yu, Ho Seok Chung, Do Gyeong Lim, Sun-Ouck Kim   +3 more
doaj   +2 more sources

Caveolins and macrophage lipid metabolism

Journal of Lipid Research, 2003
The identification of caveolin-1 more than a decade ago initiated active research into its role in the formation of caveolae, membrane trafficking, signal transduction pathways, and lipid homeostasis.
Ladislav Dory
exaly   +3 more sources

A model for membrane curvature generation by caveolin discs driven by differential contact interaction [PDF]

Nature Communications
The recent discovery of the flat, disc-like structure of caveolin oligomers, predicted to be embedded in one membrane leaflet, has challenged earlier models of membrane curvature generation by caveolins during caveola biogenesis.
Avishai Barnoy, Nicholas Ariotti, Robert G. Parton, Michael M. Kozlov   +3 more
doaj   +2 more sources

Therapeutic role of caveolin family in stem cell fate and development for management of chronic degenerative diseases: A scientometric study to an in-depth review [PDF]

Journal of Advanced Research
Background: Caveolins (CAV), a family of integral membrane proteins, are involved in regulating stem cell fate, which are critical for tissue repair and regeneration. Drawing from scientometric studies and comprehensive research, this review investigates
Ruishuang Ma, Shuang Wang, Yuan-Lu Cui, Han Zhang, Xiaopeng Chen, Jinbing Xie, Yue Li   +6 more
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Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation [PDF]

Journal of Cell Biology, 2023
Frédéric Morales-Paytuvi, Albert Pol, Brett Collins   +2 more
exaly   +2 more sources

Evolutionarily diverse caveolins share a common structural framework built around amphipathic disks [PDF]

Journal of Cell Biology
Louis F L Wilson, Erkan Karakas, Anne Kenworthy   +2 more
exaly   +2 more sources

Editorial: Caveolins in inflammation, infections, and disease [PDF]

Frontiers in Immunology
Stanley Hoffman, Clarissa M. Maya-Monteiro, Cecilia J. G. de Almeida   +2 more
doaj   +2 more sources