Results 1 to 10 of about 65,797 (247)

Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1 [PDF]

BMC Infectious Diseases, 2004
Background Lipid raft domains form in plasma membranes of eukaryotic cells by the tight packing of glycosphingolipids and cholesterol. Caveolae are invaginated structures that form in lipid raft domains when the protein caveolin-1 is expressed.
Norkin Leonard C, Webley Wilmore C, Stuart Elizabeth S   +2 more
doaj   +4 more sources

Caveolin-1 is a critical determinant of autophagy, metabolic switching, and oxidative stress in vascular endothelium. [PDF]

PLoS ONE, 2014
Caveolin-1 is a scaffolding/regulatory protein that interacts with diverse signaling molecules. Caveolin-1(null) mice have marked metabolic abnormalities, yet the underlying molecular mechanisms are incompletely understood.
Takashi Shiroto, Natalia Romero, Toru Sugiyama, Juliano L Sartoretto, Hermann Kalwa, Zhonghua Yan, Hiroaki Shimokawa, Thomas Michel   +7 more
doaj   +6 more sources

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion [PDF]

Cancer Cell, 2003
EGF receptor (EGFR) overexpression correlates with metastasis in a variety of carcinomas, but the underlying mechanisms are poorly understood. We demonstrated that EGF disrupted cell-cell adhesion and caused epithelial-to-mesenchymal transition (EMT) in ...
Zhimin Lu, Sourav Ghosh, Tony Hunter
exaly   +3 more sources

Decreased Expression of Urethral Caveolin-1, −2, and −3 in the Rat Model of Overactive Bladder: Potential Mediator of Functional Interaction of Urethra and Urinary Bladder [PDF]

International Neurourology Journal, 2023
Purpose To investigate the effect of detrusor overactivity (DO) on the urethral expression of caveolin (CAV)-1, −2, and −3 of urethra in an animal model of cyclophosphamide (CYP)-induced cystitis rat.
Hyun Jin Cho, Han-Yi Jiao, Sun-Ouck Kim
doaj   +1 more source

Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival

Frontiers in Cellular Neuroscience, 2023
Introduction: Caveolin-1 and Caveolin-2 (CAV1 and CAV2) are proteins associated with intercellular neurotrophic signalling. There is converging evidence that CAV1 and CAV2 (CAV1/2) genes have a role in amyotrophic lateral sclerosis (ALS).
Brett N. Adey, Brett N. Adey, Johnathan Cooper-Knock, Ahmad Al Khleifat, Isabella Fogh, Philip van Damme, Philip van Damme, Philip van Damme, Philippe Corcia, Philippe Corcia, Philippe Couratier, Philippe Couratier, Orla Hardiman, Russell McLaughlin, Marc Gotkine, Marc Gotkine, Vivian Drory, Vivian Drory, Vincenzo Silani, Vincenzo Silani, Nicola Ticozzi, Nicola Ticozzi, Jan H. Veldink, Leonard H. van den Berg, Mamede de Carvalho, Susana Pinto, Jesus S. Mora Pardina, Mónica Povedano Panades, Peter M. Andersen, Markus Weber, Nazli A. Başak, Christopher E. Shaw, Pamela J. Shaw, Karen E. Morrison, John E. Landers, Jonathan D. Glass, Patrick Vourc’h, Patrick Vourc’h, Richard J. B. Dobson, Richard J. B. Dobson, Richard J. B. Dobson, Richard J. B. Dobson, Gerome Breen, Ammar Al-Chalabi, Ammar Al-Chalabi, Ashley R. Jones, Alfredo Iacoangeli, Alfredo Iacoangeli, Alfredo Iacoangeli   +48 more
doaj   +1 more source

#123 : Caveolin-1 Function and Regulation in Mouse Uterus During Early Pregnancy and Under Human In Vitro Decidualization

Fertility & Reproduction, 2023
Background and Aims: Endometrial decidualization is a step in establishing and maintaining pregnancy. Senescence was considered to accompany with decidualization.
Song Zhuo
doaj   +1 more source

Caveolins in rhabdomyosarcoma [PDF]

Journal of Cellular and Molecular Medicine, 2011
Caveolins are scaffolding proteins that play a pivotal role in numerous processes, including caveolae biogenesis, vesicular transport, cholesterol homeostasis and regulation of signal transduction. There are three different isoforms (Cav-1, -2 and -3) that form homo- and hetero-aggregates at the plasma membrane and modulate the activity of a number of ...
Rossi, Stefania, Poliani, Pietro Luigi, Missale, Cristina, Monti, Eugenio, Fanzani, Alessandro   +4 more
openaire   +5 more sources

M‐caveolin, a muscle‐specific caveolin‐related protein [PDF]

FEBS Letters, 1995
Caveolae, small invaginations of the plasma membrane, are a characteristic feature of many mammalian cells. The best‐characterised caveolar protein is the integral membrane protein, VIP21‐caveolin. We now describe a novel homologue of VIP21‐caveolin, M‐caveolin, which is expressed exclusively in muscle.
Way, Michael, Parton, Robert G.
openaire   +5 more sources

Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells. [PDF]

PLoS ONE, 2012
Caveolin-1 is known to promote cell migration, and increased caveolin-1 expression is associated with tumor progression and metastasis. In fibroblasts, caveolin-1 polarization and phosphorylation of tyrosine-14 are essential to promote migration. However,
Hery Urra, Vicente A Torres, Rina J Ortiz, Lorena Lobos, María I Díaz, Natalia Díaz, Steffen Härtel, Lisette Leyton, Andrew F G Quest   +8 more
doaj   +1 more source

Lifestyle intervention in individuals with impaired glucose regulation affects Caveolin-1 expression and DNA methylation [PDF]

, 2020
© 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impaired ...
Adam, S., Dalton, Caroline, Donn, R.P., Fachim, H.A., Gibson, J.M., Heald, A.H., Malipatil, N., Moreno, G.Y.C., Siddals, K., Soran, H.   +9 more
core   +1 more source