Results 1 to 10 of about 41,045 (251)

Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1 [PDF]

BMC Infectious Diseases, 2004
Background Lipid raft domains form in plasma membranes of eukaryotic cells by the tight packing of glycosphingolipids and cholesterol. Caveolae are invaginated structures that form in lipid raft domains when the protein caveolin-1 is expressed.
Norkin Leonard C, Webley Wilmore C, Stuart Elizabeth S   +2 more
doaj   +7 more sources

Expression of Caveolin-1, Caveolin-2 and Caveolin-3 in Thyroid Cancer and Stroma [PDF]

Pathobiology, 2012
<i>Objective:</i> To study the expression status of caveolin-1, caveolin-2 and caveolin-3 in the epithelial and stromal compartments of conventional papillary thyroid carcinoma (PTC), diffuse sclerosing variant of papillary carcinoma (DSVPC) and anaplastic carcinoma (AC).
Dokyung, Kim, Haeryoung, Kim, Ja Seung, Koo   +2 more
core   +6 more sources

Identification of Caveolin and Caveolin-Related Proteins in the Brain [PDF]

The Journal of Neuroscience, 1997
Caveolae are 50–100 nm, nonclathrin-coated, flask-shaped plasma membrane microdomains that have been identified in most mammalian cell types, except lymphocytes and neurons. To date, multiple functions have been ascribed to caveolae, including the compartmentalization of lipid and protein components that function in transmembrane signaling events ...
P L, Cameron, J W, Ruffin, R, Bollag, H, Rasmussen, R S, Cameron   +4 more
openaire   +4 more sources

Upregulation of aquaporin-2 and caveolins in rat bladder with outlet obstruction-induced detrusor overactivity [PDF]

Investigative and Clinical Urology
Purpose: Bladder outlet obstruction (BOO) leads to detrusor overactivity (DO) and structural remodeling of the bladder. However, the molecular mechanisms underlying this process remain incompletely understood.
Seong Hyeon Yu, Ho Seok Chung, Do Gyeong Lim, Sun-Ouck Kim   +3 more
doaj   +2 more sources

Caveolin 2 [PDF]

AfCS-Nature Molecule Pages, 2006
Caveolin-2 may act as a scaffolding protein within caveolar/lipid raft membranes. Caveolin-2 forms stable hetero-oligomeric complexes with caveolin-1 in many cell types, including fibroblastic cells. Caveolin-2 can also interact with caveolin-3, the striated muscle-specific isoform, when co-expressed in muscle cells.
Ostrom, Rennolds S.
openaire   +4 more sources

Regulation of caveolin and caveolae by cholesterol in MDCK cells

Journal of Lipid Research, 1998
We have examined the expression of caveolin in MDCK cells under conditions that vary cellular cholesterol concentration. Caveolin mRNA levels dropped to one-sixth of control levels after treatment with simvastatin, an inhibitor of cholesterol synthesis ...
Robert Parton
exaly   +3 more sources

Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond [PDF]

Frontiers in Immunology, 2017
Caveolins, encoded by the CAV gene family, are the main protein components of caveolae. In most tissues, caveolin-1 (Cav-1) and caveolin-2 (Cav-2) are co-expressed, and Cav-2 targeting to caveolae depends on the formation of heterooligomers with Cav-1 ...
Cecília Jacques Gonçalves de Almeida
doaj   +3 more sources

Decreased Expression of Urethral Caveolin-1, −2, and −3 in the Rat Model of Overactive Bladder: Potential Mediator of Functional Interaction of Urethra and Urinary Bladder [PDF]

International Neurourology Journal, 2023
Purpose To investigate the effect of detrusor overactivity (DO) on the urethral expression of caveolin (CAV)-1, −2, and −3 of urethra in an animal model of cyclophosphamide (CYP)-induced cystitis rat.
Hyun Jin Cho, Han-Yi Jiao, Sun-Ouck Kim
doaj   +1 more source

Caveolins in rhabdomyosarcoma [PDF]

Journal of Cellular and Molecular Medicine, 2011
Caveolins are scaffolding proteins that play a pivotal role in numerous processes, including caveolae biogenesis, vesicular transport, cholesterol homeostasis and regulation of signal transduction. There are three different isoforms (Cav-1, -2 and -3) that form homo- and hetero-aggregates at the plasma membrane and modulate the activity of a number of ...
Rossi, Stefania, Poliani, Pietro Luigi, Missale, Cristina, Monti, Eugenio, Fanzani, Alessandro   +4 more
openaire   +5 more sources

Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival

Frontiers in Cellular Neuroscience, 2023
Introduction: Caveolin-1 and Caveolin-2 (CAV1 and CAV2) are proteins associated with intercellular neurotrophic signalling. There is converging evidence that CAV1 and CAV2 (CAV1/2) genes have a role in amyotrophic lateral sclerosis (ALS).
Brett N. Adey, Brett N. Adey, Johnathan Cooper-Knock, Ahmad Al Khleifat, Isabella Fogh, Philip van Damme, Philip van Damme, Philip van Damme, Philippe Corcia, Philippe Corcia, Philippe Couratier, Philippe Couratier, Orla Hardiman, Russell McLaughlin, Marc Gotkine, Marc Gotkine, Vivian Drory, Vivian Drory, Vincenzo Silani, Vincenzo Silani, Nicola Ticozzi, Nicola Ticozzi, Jan H. Veldink, Leonard H. van den Berg, Mamede de Carvalho, Susana Pinto, Jesus S. Mora Pardina, Mónica Povedano Panades, Peter M. Andersen, Markus Weber, Nazli A. Başak, Christopher E. Shaw, Pamela J. Shaw, Karen E. Morrison, John E. Landers, Jonathan D. Glass, Patrick Vourc’h, Patrick Vourc’h, Richard J. B. Dobson, Richard J. B. Dobson, Richard J. B. Dobson, Richard J. B. Dobson, Gerome Breen, Ammar Al-Chalabi, Ammar Al-Chalabi, Ashley R. Jones, Alfredo Iacoangeli, Alfredo Iacoangeli, Alfredo Iacoangeli   +48 more
doaj   +1 more source