Results 11 to 20 of about 57,111 (301)
Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1 [PDF]
BMC Infectious Diseases, 2004 Background Lipid raft domains form in plasma membranes of eukaryotic cells by the tight packing of glycosphingolipids and cholesterol. Caveolae are invaginated structures that form in lipid raft domains when the protein caveolin-1 is expressed.
Norkin Leonard C +2 more
doaj +7 more sources
Expression of Caveolin-1, Caveolin-2 and Caveolin-3 in Thyroid Cancer and Stroma [PDF]
Pathobiology, 2012 <i>Objective:</i> To study the expression status of caveolin-1, caveolin-2 and caveolin-3 in the epithelial and stromal compartments of conventional papillary thyroid carcinoma (PTC), diffuse sclerosing variant of papillary carcinoma (DSVPC) and anaplastic carcinoma (AC).
Dokyung, Kim +2 more
core +4 more sources
Identification of Caveolin and Caveolin-Related Proteins in the Brain [PDF]
The Journal of Neuroscience, 1997 Caveolae are 50–100 nm, nonclathrin-coated, flask-shaped plasma membrane microdomains that have been identified in most mammalian cell types, except lymphocytes and neurons. To date, multiple functions have been ascribed to caveolae, including the compartmentalization of lipid and protein components that function in transmembrane signaling events ...
P L, Cameron +4 more
openaire +3 more sources
AfCS-Nature Molecule Pages, 2006 Caveolin-2 may act as a scaffolding protein within caveolar/lipid raft membranes. Caveolin-2 forms stable hetero-oligomeric complexes with caveolin-1 in many cell types, including fibroblastic cells. Caveolin-2 can also interact with caveolin-3, the striated muscle-specific isoform, when co-expressed in muscle cells.
Ostrom, Rennolds S.
openaire +3 more sources
Caveolins in rhabdomyosarcoma [PDF]
Journal of Cellular and Molecular Medicine, 2011 Caveolins are scaffolding proteins that play a pivotal role in numerous processes, including caveolae biogenesis, vesicular transport, cholesterol homeostasis and regulation of signal transduction. There are three different isoforms (Cav-1, -2 and -3) that form homo- and hetero-aggregates at the plasma membrane and modulate the activity of a number of ...
Rossi, Stefania +4 more
openaire +5 more sources
Caveolin-1–eNOS Signaling Promotes p190RhoGAP-A Nitration and Endothelial Permeability [PDF]
, 2011 Endothelial barrier function is regulated by adherens junctions (AJs) and caveolae-mediated transcellular pathways. The opening of AJs that is observed in caveolin-1-/- (Cav-1-/-) endothelium suggests that Cav-1 is necessary for AJ assembly or ...
Yulia A. Komarova (7945946) +8 more
core +7 more sources
Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae
Journal of Cell Biology, 2021 We integrated quantitative nanoscale lipid mapping with molecular dynamic simulations to define the lipid profile within caveolae. Caveolin-1 and cavin1 individually sort distinct plasma membrane lipids.
Yong Zhou +11 more
semanticscholar +1 more source
Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells. [PDF]
PLoS ONE, 2012 Caveolin-1 is known to promote cell migration, and increased caveolin-1 expression is associated with tumor progression and metastasis. In fibroblasts, caveolin-1 polarization and phosphorylation of tyrosine-14 are essential to promote migration. However,
Hery Urra +8 more
doaj +1 more source
Cell Death and Disease, 2020 Aflatoxin B1 (AFB1) is a potent hepatocarcinogen in humans and exposure to AFB1 is known to cause both acute and chronic hepatocellular injury. As the liver is known to be the main target organ of aflatoxin, it is important to identify the key molecules ...
Qing-Qiang Xu +12 more
semanticscholar +1 more source
, 2013 Objective:Immunosuppression is cornerstone treatment of antineutrophil cytoplasmic antibody associated vasculitis (AAV) but is later complicated by infection, cancer, cardiovascular and chronic kidney disease.
Matthew Simmonds (17167288) +12 more
core +5 more sources