Results 41 to 50 of about 57,111 (301)
, 2016 BACKGROUND: Arteriosclerosis is an independent predictor of increased cardiovascular mortality in chronic kidney disease (CKD). Histologically it is characterized by hypertrophy and fibrosis of the arterial media wall leading to increased arterial ...
C.J. Ferro (17225302) +12 more
core +5 more sources
Journal of Pharmacological Sciences, 2008 Caveolin-1 is a principal component of caveolae, invaginations of the plasma membrane that are enriched in cholesterol and sphingolipids. The expression of caveolin-1 has been shown to be tightly correlated to the progression of breast cancer tumors ...
Hua Zhu +4 more
doaj +1 more source
Biomedicines, 2023 A short synthetic peptide from the C-terminal part of the caveolin-3 structure was tested for experimental autoimmune encephalomyelitis (EAE) treatment in rats.
Alexey V. Danilkovich +18 more
doaj +1 more source
The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1
Biomolecules, 2019 Stress-induced premature cellular senescence is a significant factor in the onset of age-dependent disease in the cardiovascular system. Plasminogen activator inhibitor-1 (PAI-1), a major TGF-β1/p53 target gene and negative regulator of the plasmin-based
R. Samarakoon +3 more
semanticscholar +1 more source
Microorganisms, 2022 Mutualistic bacteria have different forms of interaction with the host. In contrast to the invasion of pathogenic bacteria, naturally occurring internalization of commensal bacteria has not been studied in depth.
Diana Aurora Ramirez-Sánchez +5 more
doaj +1 more source
Decreased urothelial expression of caveolin 1 and 2 in aging rats showing detrusor overactivity: Potential association with aging bladder [PDF]
Investigative and Clinical Urology, 2021 Purpose: The purpose of this study was to investigate the effect of aging on bladder function and caveolin protein expression in rat urothelium. Materials and Methods: Female Sprague-Dawley rats were divided into the following two groups: young age ...
Jae Hyeon Kim +2 more
doaj +1 more source
Caveolin-1 expression in benign and malignant lesions of the breast
World Journal of Surgical Oncology, 2007 Background Caveolin-1 is thought to have an important impact on both signal transduction and mediation of intracellular processes. Furthermore, it has been suggested that Caveolin-1 may contribute to certain steps of carcinogenesis in various types of ...
Kiesel Ludwig +4 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Introduction: Extensive studies indicated that caveolin is a key regulator in multiple cellular processes. Recently, growing evidence demonstrated that caveolin is critically involved in tumor progression.
Yaqian Tan, Qi Song
doaj +1 more source
Caveolin-1 in the regulation of cell metabolism: a cancer perspective
Molecular Cancer, 2016 Caveolin-1 (CAV1) is an oncogenic membrane protein associated with endocytosis, extracellular matrix organisation, cholesterol distribution, cell migration and signaling.
Z. Nwosu, M. Ebert, S. Dooley, C. Meyer
semanticscholar +1 more source
Getting rid of caveolins: Phenotypes of caveolin-deficient animals
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2005 The elucidation of the role of caveolae has been the topic of many investigations which were greatly enhanced after the discovery of caveolin, the protein marker of these flask-shaped plasma membrane invaginations. The generation of mice deficient in the various caveolin genes (cav-1, cav-2 and cav-3) has provided physiological models to unravel the ...
Le Lay, S., Kurzchalia, T.
openaire +3 more sources