Results 51 to 60 of about 57,111 (301)
OncoTarget, 2017 Hyperphosphorylation of Tau forming neurofibrillary tangles has been considered as a crucial event in the pathogenesis of Alzheimer's disease (AD). MiR-124-3p belongs to microRNA (miRNA) family and was markedly decreased in AD, however, the functions of ...
Qingmei Kang +11 more
semanticscholar +1 more source
Dose-Response, 2020 Objective: The aim of this study was to evaluate the levels of caveolin-1 in thyroid follicular epithelial cells of papillary thyroid cancer, follicular thyroid cancer, and nonmalignant thyroid nodule benign follicular adenoma, as well as to explore the ...
Jingyi Zhang +7 more
doaj +1 more source
Oncogene, 2017 N-myc downstream-regulated gene 1 (NDRG1) has been reported to act as a key regulatory molecule in tumor progression-related signaling pathways, especially in tumor metastasis. However, the related mechanism has not been fully discovered yet.
L. Mi +11 more
semanticscholar +1 more source
Scientific Reports, 2017 Caveolae are abundant flask-shaped invaginations of plasma membranes that buffer membrane tension through their deformation. Few quantitative studies on the deformation of caveolae have been reported.
Masashi Tachikawa +6 more
doaj +1 more source
Caveolin-1 expression in different types of psoriatic lesions: Analysis of 66 cases
Indian Journal of Dermatology, 2014 Background: Caveolin-1 is a key structural and functional protein. Caveolin-1 is known to modulate multiple signal-transducing pathways involved in cell differentiation and proliferation. Psoriasis is viewed as a multifactorial pathology characterized by
Feng Zhang +4 more
doaj +1 more source
Membrane Compartmentalization and Scaffold Proteins in Leukocyte Migration
Frontiers in Cell and Developmental Biology, 2020 Leukocyte migration across vessels into and within peripheral and lymphoid tissues is essential for host defense against invading pathogens. Leukocytes are specialized in sensing a variety of guidance cues and to integrate environmental stimuli to ...
Guerric P. B. Samson +3 more
doaj +1 more source
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
Nature Communications, 2016 Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. The identification of cancer cell internalizing antigens for drug targeting to the hypoxic tumour niche remains a challenge of high clinical relevance.
E. Bourseau-Guilmain +9 more
semanticscholar +1 more source
Tumor Biology, 2017 Despite the consolidated clinico-pathological correlates of Caveolin 1 expression in non–small cell lung cancer, the available data on the role of Caveolin 1 in relation to proliferation, migration, and metastasis in lung adenocarcinoma cells is still ...
Eleonora Duregon +8 more
doaj +1 more source
Metformin-induced caveolin-1 expression promotes T-DM1 drug efficacy in breast cancer cells
Scientific Reports, 2018 Trastuzumab emtansine (T-DM1) is an antibody drug conjugate (ADC) that was recently approved for the treatment of HER-2-positive metastatic breast cancer. The drug sensitivity of ADCs depends mainly on the internalization efficiency of the drug. Caveolin-
Yuan-Chiang Chung +5 more
semanticscholar +1 more source
Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1-0
, 2011 Copyright information:Taken from "Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1"BMC Infectious Diseases 2004;4():23-23.Published online 22 Jul 2004PMCID:PMC497042.Copyright © 2004 Webley et al; licensee BioMed
Leonard C Norkin (4287) +2 more
core +1 more source