Results 31 to 40 of about 57,111 (301)
Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli
Journal of Experimental Medicine, 2019 Extracellular vesicle (EV)–cargo miRNAs mediate intercellular communications. How cells selectively sort the miRNAs into EVs remains unclear. Lee et al. demonstrate a novel mechanism by which functional miRNAs are selectively sorted into EVs via caveolin-
Heedoo Lee +5 more
semanticscholar +1 more source
Caveolins and Lung Function [PDF]
, 2012 The primary function of the mammalian lung is to facilitate diffusion of oxygen to venous blood and to ventilate carbon dioxide produced by catabolic reactions within cells. However, it is also responsible for a variety of other important functions, including host defense and production of vasoactive agents to regulate not only systemic blood pressure,
Maniatis, N.A. +3 more
openaire +3 more sources
Energy and Dynamics of Caveolae Trafficking
Frontiers in Cell and Developmental Biology, 2021 Caveolae are 70–100 nm diameter plasma membrane invaginations found in abundance in adipocytes, endothelial cells, myocytes, and fibroblasts. Their bulb-shaped membrane domain is characterized and formed by specific lipid binding proteins including ...
Claudia Matthaeus, Justin W. Taraska
doaj +1 more source
Journal of Lipid Research, 2010 Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin +12 more
doaj +1 more source
Loss of Caveolin 1 is Associated With the Expression of Aquaporin 1 and Bladder Dysfunction in Mice [PDF]
International Neurourology Journal, 2015 Purpose: It is suggested that caveolin and aquaporin might be closely associated with bladder signal activity. We investigated the effect of the deletion of caveolin 1, using caveolin 1 knockout mice, on the expression of aquaporin 1 in order to identify
Seheon Jung +6 more
doaj +1 more source
Journal of the Egyptian National Cancer Institute, 2017 Caveolin-1 may play a role in cancer development and progression. The aim was to record the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high grade prostatic intraepithelial neoplasia (HGPIN) and prostatic carcinoma ...
Dareen A. Mohammed, Duaa S. Helal
doaj +1 more source
Caveolin-1 expression is elevated in claudin-low mammary tumor cells
Cancer Cell International, 2012 Background Caveolin-1 is a scaffolding protein found in plasma membrane invaginations known as caveolae. Caveolin-1 can regulate a number of intracellular processes such as signal transduction, cholesterol metabolism and vesicular transport. With respect
Thompson Devan E +2 more
doaj +1 more source
Microglial Activation Plays a Critical Role in LPS-Induced Contextual Fear Memory Consolidation Impairment and Blood-Brain Barrier Disruption. [PDF]
Brain BehavABSTRACT Background Accurately predicting environmental dangers is a fundamental ability for animal and human survival. Fear memory could be disrupted by various stimuli, including inflammation, which can be mimicked by lipopolysaccharide (LPS) injection. LPS, which can activate microglia and disrupt the blood‐brain barrier (BBB), can impair contextual
Zheng J, Li L, Jin X, Liu W.
europepmc +2 more sources
Caveolin-1 in Tumour Cells is Predominately Expressed in the Basal Subtype of Triple-Negative Breast Carcinoma [PDF]
Journal of Biomedical & Clinical Research, 2014 Triple-negative breast cancer (TNBC) is a subtype of breast cancer which is clinically negative for expression of steroid hormones and HER2 protein.
Savelina Popovska +2 more
doaj +3 more sources
Theoretical model for the formation of caveolae and similar membrane invaginations [PDF]
, 2004 We study a physical model for the formation of bud-like invaginations on fluid lipid membranes under tension, and apply this model to caveolae formation.
Turner, Matthew S. +2 more
core +1 more source