Results 21 to 30 of about 65,797 (247)

Caveolins and Lung Function [PDF]

open access: yes, 2012
The primary function of the mammalian lung is to facilitate diffusion of oxygen to venous blood and to ventilate carbon dioxide produced by catabolic reactions within cells. However, it is also responsible for a variety of other important functions, including host defense and production of vasoactive agents to regulate not only systemic blood pressure,
Maniatis, N.A.   +3 more
openaire   +3 more sources

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects[S]

open access: yesJournal of Lipid Research, 2010
Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin   +12 more
doaj   +1 more source

Loss of Caveolin 1 is Associated With the Expression of Aquaporin 1 and Bladder Dysfunction in Mice [PDF]

open access: yesInternational Neurourology Journal, 2015
Purpose: It is suggested that caveolin and aquaporin might be closely associated with bladder signal activity. We investigated the effect of the deletion of caveolin 1, using caveolin 1 knockout mice, on the expression of aquaporin 1 in order to identify
Seheon Jung   +6 more
doaj   +1 more source

Prognostic significance of epithelial/stromal caveolin‐1 expression in prostatic hyperplasia, high grade prostatic intraepithelial hyperplasia and prostatic carcinoma and its correlation with microvessel density

open access: yesJournal of the Egyptian National Cancer Institute, 2017
Caveolin-1 may play a role in cancer development and progression. The aim was to record the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high grade prostatic intraepithelial neoplasia (HGPIN) and prostatic carcinoma ...
Dareen A. Mohammed, Duaa S. Helal
doaj   +1 more source

Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure [PDF]

open access: yes, 2016
RATIONALE: In heart failure, myofilament proteins display abnormal phosphorylation, which contributes to contractile dysfunction. The mechanisms underlying the dysregulation of protein phosphorylation on myofilaments is not clear.
Barbagallo, Federica   +15 more
core   +1 more source

Caveolin Revealed: A Mutagenesis Study of Caveolin-1 [PDF]

open access: yesBiophysical Journal, 2015
Caveolae are 50-100 nm invaginations in the plasma membrane that are rich in cholesterol, sphingomyelin and the integral membrane protein called caveolin-1. Caveolin-1 has three main functions: forming caveolae, cell signaling, and endocytosis. To examine the importance of conserved residues within the scaffolding and intra-membrane domains of caveolin-
Plucinsky, Sarah, Glover, Kerney J.
openaire   +1 more source

Caveolin-1 expression is elevated in claudin-low mammary tumor cells

open access: yesCancer Cell International, 2012
Background Caveolin-1 is a scaffolding protein found in plasma membrane invaginations known as caveolae. Caveolin-1 can regulate a number of intracellular processes such as signal transduction, cholesterol metabolism and vesicular transport. With respect
Thompson Devan E   +2 more
doaj   +1 more source

Caveolin-1 in Tumour Cells is Predominately Expressed in the Basal Subtype of Triple-Negative Breast Carcinoma [PDF]

open access: yesJournal of Biomedical & Clinical Research, 2014
Triple-negative breast cancer (TNBC) is a subtype of breast cancer which is clinically negative for expression of steroid hormones and HER2 protein.
Savelina Popovska   +2 more
doaj   +3 more sources

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]

open access: yes, 2013
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
A Bist   +103 more
core   +4 more sources

C-Terminal Region of Caveolin-3 Contains a Stretch of Amino Acid Residues Capable of Diminishing Symptoms of Experimental Autoimmune Encephalomyelitis but Not Rheumatoid Arthritis Modeled in Rats

open access: yesBiomedicines, 2023
A short synthetic peptide from the C-terminal part of the caveolin-3 structure was tested for experimental autoimmune encephalomyelitis (EAE) treatment in rats.
Alexey V. Danilkovich   +18 more
doaj   +1 more source

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