Caveolin-1 promotes tumor cell proliferation and vasculogenic mimicry formation in human glioma [PDF]
, 2021 Vasculogenic mimicry (VM) plays an important role in human glioma progression and resistance to antiangiogenic therapy as a compensatory neovascularization mechanism in malignant tumors.
Wenjie Hu (2698855) +5 more
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Caveolins and Lung Function [PDF]
, 2012 The primary function of the mammalian lung is to facilitate diffusion of oxygen to venous blood and to ventilate carbon dioxide produced by catabolic reactions within cells. However, it is also responsible for a variety of other important functions, including host defense and production of vasoactive agents to regulate not only systemic blood pressure,
Maniatis, N.A. +3 more
openaire +3 more sources
Oxldl Upregulates Caveolin-1 Expression in Macrophages: Role for Caveolin- 1 in the Adhesion of Oxldl-Treated Macrophages to Endothelium [PDF]
, 2011 Caveolin-1, a principle component of caveolae, is present in several cell types known to play an important role in the development of atherosclerosis.
吳造中;王淑慧;管奕奕;曾維功;陳明豐;吳建春;陳玉怜 +1 more
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Interaction of caveolin-1 with Ku70 inhibits Bax-mediated apoptosis. [PDF]
PLoS ONE, 2012 Caveolin-1, the structural protein component of caveolae, acts as a scaffolding protein that functionally regulates signaling molecules. We show that knockdown of caveolin-1 protein expression enhances chemotherapeutic drug-induced apoptosis and inhibits
Huafei Zou +2 more
doaj +1 more source
Association/Dissociation of Caveolin-1 and Nitric Oxide Synthase in Preserving Renal Medulla Function during Hemorrhage and Aging [PDF]
, 2021 Background: Caveolin-1 is a negative regulator of endothelial nitric oxide synthase (eNOS), as its interaction and binding suppress the activityof eNOS by making caveolin–eNOS complex.
Balaszczuk, Ana María +4 more
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Energy and Dynamics of Caveolae Trafficking
Frontiers in Cell and Developmental Biology, 2021 Caveolae are 70–100 nm diameter plasma membrane invaginations found in abundance in adipocytes, endothelial cells, myocytes, and fibroblasts. Their bulb-shaped membrane domain is characterized and formed by specific lipid binding proteins including ...
Claudia Matthaeus, Justin W. Taraska
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Journal of Lipid Research, 2010 Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin +12 more
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Loss of Caveolin 1 is Associated With the Expression of Aquaporin 1 and Bladder Dysfunction in Mice [PDF]
International Neurourology Journal, 2015 Purpose: It is suggested that caveolin and aquaporin might be closely associated with bladder signal activity. We investigated the effect of the deletion of caveolin 1, using caveolin 1 knockout mice, on the expression of aquaporin 1 in order to identify
Seheon Jung +6 more
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Caveolin-1 Expression Is Significantly Associated with Drug Resistance and Poor Prognosis in Advanced Non-Small Cell Lung Cancer Patients Treated with Gemcitabine-Based Chemotherapy [PDF]
, 2011 Caveolin-1 was up-regulated in different drug-resistant cancer cell tines and was suggested to confer drug resistance by different mechanisms. However, the relation of caveolin-1 expression and the clinical response to chemotherapy and prognosis in non ...
何肇基;郭頌鑫;黃佩欣;黃馨儀;楊志新;楊泮池 +1 more
core +1 more source
Journal of the Egyptian National Cancer Institute, 2017 Caveolin-1 may play a role in cancer development and progression. The aim was to record the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high grade prostatic intraepithelial neoplasia (HGPIN) and prostatic carcinoma ...
Dareen A. Mohammed, Duaa S. Helal
doaj +1 more source