Results 21 to 30 of about 6,074 (242)
Caveolae as Potential Hijackable Gates in Cell Communication
Frontiers in Cell and Developmental Biology, 2020 Caveolae are membrane microdomains described in many cell types involved in endocytocis, transcytosis, cell signaling, mechanotransduction, and aging. They are found at the interface with the extracellular environment and are structured by caveolin and ...
Maria Dudãu +10 more
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Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]
, 2019 PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ +7 more
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Caveolin-3 differentially orchestrates cholinergic and serotonergic constriction of murine airways [PDF]
, 2018 The mechanisms of controlling airway smooth muscle (ASM) tone are of utmost clinical importance as inappropriate constriction is a hallmark in asthma and chronic obstructive pulmonary disease.
Hollenhorst, M. I. +7 more
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Dynamic and Regulated Association of Caveolin with Lipid Bodies: Modulation of Lipid Body Motility and Function by a Dominant Negative Mutant [PDF]
, 2003 Caveolins are a crucial component of caveolae but have also been localized to the Golgi complex, and, under some experimental conditions, to lipid bodies (LBs). The physiological relevance and dynamics of LB association remain unclear.
Carozzi, Amanda +7 more
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Nature Communications, 2022 Caveolae are small coated plasma membrane invaginations with diverse functions. Caveolae undergo curvature changes. Yet, it is unclear which proteins regulate this process. To address this gap, we develop a correlative stimulated emission depletion (STED)
Claudia Matthaeus +6 more
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Caveolins and Lung Function [PDF]
, 2012 The primary function of the mammalian lung is to facilitate diffusion of oxygen to venous blood and to ventilate carbon dioxide produced by catabolic reactions within cells. However, it is also responsible for a variety of other important functions, including host defense and production of vasoactive agents to regulate not only systemic blood pressure,
Maniatis, N.A. +3 more
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Brain Sciences, 2012 Caveolin is the principal protein of caveolae and has been implicated in the pathogenesis of cerebral ischemia. To investigate whether changed expression of caveolins has a pivotal role in focal cerebral ischemia, we induced middle cerebral artery ...
Yonggeun Hong +9 more
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Translocation of caveolin regulates stretch-induced ERK activity in vascular smooth muscle [PDF]
, 2004 Kawabe, J; Okumura, S; Lee, MC; Sadoshima, J; Ishikawa, Y, AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 286(5), H1845-H1852, 2004. "Copyright 2004 by the American Physical Society." publisherMechanical stress contributes to vascular ...
Ishikawa, Y +6 more
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Rosiglitazone drives cavin-2/SDPR expression in adipocytes in a CEBPα-dependent manner. [PDF]
PLoS ONE, 2017 Caveolae are abundant adipocyte surface domains involved in insulin signaling, membrane trafficking and lipid homeostasis. Transcriptional control mechanisms for caveolins and cavins, the building blocks of caveolae, are thus arguably important for ...
Björn Hansson +7 more
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Caveolin Revealed: A Mutagenesis Study of Caveolin-1 [PDF]
Biophysical Journal, 2015 Caveolae are 50-100 nm invaginations in the plasma membrane that are rich in cholesterol, sphingomyelin and the integral membrane protein called caveolin-1. Caveolin-1 has three main functions: forming caveolae, cell signaling, and endocytosis. To examine the importance of conserved residues within the scaffolding and intra-membrane domains of caveolin-
Plucinsky, Sarah, Glover, Kerney J.
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