Results 31 to 40 of about 6,074 (242)
Journal of Lipid Research, 1999 SW-13 adrenal tumor cells that lack detectable intermediate filaments (IF-free) exhibit an impaired capacity to esterify lipoprotein-derived cholesterol compared with cells that contain vimentin filaments.
Tricia A. Holwell +3 more
doaj +1 more source
Caveolae and Lipid Rafts in Endothelium: Valuable Organelles for Multiple Functions
Biomolecules, 2020 Caveolae are flask-shaped invaginations of the plasma membrane found in numerous cell types and are particularly abundant in endothelial cells and adipocytes.
Antonio Filippini, Alessio D’Alessio
doaj +1 more source
Age-related influence of hypothyroidism on caveolins and nitric oxide modulation [PDF]
, 2014 Introduction: Hypothyroidism and age impact on cardiac and renal nitricoxide (NO) production. Caveolins, which are negativemodulators of NO synthase (NOS) activity, are affected byboth factors.
Arreche, Noelia Daniela +6 more
core +1 more source
Caveolin-3 and Caveolin-1 Interaction Decreases Channel Dysfunction Due to Caveolin-3 Mutations. [PDF]
Int J Mol SciCaveolae constitute membrane microdomains where receptors and ion channels functionally interact. Caveolin-3 (cav-3) is the key structural component of muscular caveolae. Mutations in CAV3 lead to caveolinopathies, which result in both muscular dystrophies and cardiac diseases. In cardiomyocytes, cav-1 participates with cav-3 to form caveolae; skeletal
Benzoni P +15 more
europepmc +7 more sources
Evaluating caveolin interactions: do proteins interact with the caveolin scaffolding domain through a widespread aromatic residue-rich motif? [PDF]
PLoS ONE, 2012 Caveolins are coat proteins of caveolae, small flask-shaped pits of the plasma membranes of most cells. Aside from roles in caveolae formation, caveolins recruit, retain and regulate many caveolae-associated signalling molecules.
Dominic P Byrne +2 more
doaj +1 more source
Role of Caveolae family-related proteins in the development of breast cancer
Frontiers in Molecular Biosciences, 2023 Breast cancer has become the most significant malignant tumor threatening women’s lives. Caveolae are concave pits formed by invagination of the plasma membrane that participate in many biological functions of the cell membrane, such as endocytosis, cell
Qinyu Han +4 more
doaj +1 more source
A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance [PDF]
, 2001 Recent studies have indicated a role for caveolin in regulating cholesterol-dependent signaling events. In the present study we have analyzed the role of caveolins in intracellular cholesterol cycling using a dominant negative caveolin mutant. The mutant
Pol, Albert +5 more
core +2 more sources
Identification of Caveolin and Caveolin-Related Proteins in the Brain [PDF]
The Journal of Neuroscience, 1997 Caveolae are 50–100 nm, nonclathrin-coated, flask-shaped plasma membrane microdomains that have been identified in most mammalian cell types, except lymphocytes and neurons. To date, multiple functions have been ascribed to caveolae, including the compartmentalization of lipid and protein components that function in transmembrane signaling events ...
P L, Cameron +4 more
openaire +2 more sources
Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]
, 2013 Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
A Bist +103 more
core +4 more sources
Journal of Lipid Research, 2010 Ectopic expression of caveolin-1 in HEK293 cells enhances FA sequestration in membranes as measured by a pH-sensitive fluorescent dye (1). We hypothesized that sequestration of FA is due to the enrichment of caveolin in the cytosolic leaflet and its ...
Jeffrey R. Simard +7 more
doaj +1 more source