Bidirectional Pathogenesis Between AD and Periodontitis. Periodontal pathogens reach the brain via hematogenous/trigeminal/oral–intestinal pathways, triggering neuroinflammation and Aβ plaques to drive AD. Conversely, AD disrupts bone homeostasis (via Aβ, endocrine/autonomic dysregulation) to aggravate periodontitis.
Weidong Zhang +5 more
wiley +1 more source
Anti‐Neuroinflammation Activity of Essential Oils and Fatty Acids
Neuroinflammation plays a pivotal role in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease (AD) and Parkinson's disease (PD). Current pharmacological interventions, such as NSAIDs and corticosteroids, are limited by systemic toxicity and insufficient efficacy in targeting chronic neuroinflammatory processes.
Zelong Jin +5 more
wiley +1 more source
Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide [PDF]
Elena Tourkina +10 more
openalex +1 more source
Caveolin-1 Genetic Polymorphisms Interact with Fatty Acid Types to Modulate Metabolic Syndrome Risk [PDF]
Faezeh Abaj, khadiheh MIRZAE
openalex +1 more source
Supplementary Figure Legends 1-6 from Caveolin-1 Regulates the Antagonistic Pleiotropic Properties of Cellular Senescence through a Novel Mdm2/p53-Mediated Pathway [PDF]
Janine N. Bartholomew +2 more
openalex +1 more source
What's new? Estrogen receptors likely influence the development of laryngeal cancer and are of particular interest in regard to their relationship with the vitamin D metabolite 24R,25(OH)2D3. In this study the authors examined interactions between 24R,25(OH)2D3 and estrogen‐responsive laryngeal tumorigenesis.
Cydney D. Dennis +10 more
wiley +1 more source
Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin–stimulated, cAMP-mediated lipolysis [PDF]
Gross, Richard W. +4 more
core +2 more sources
Microvascular Hyperpermeability in Caveolin-1 (−/−) Knock-out Mice [PDF]
William Schubert +6 more
openalex +1 more source
Cholesterol Deficiency Directs Autophagy‐Dependent Secretion of Extracellular Vesicles
Inhibition of cholesterol biosynthesis within models of rare disease and cancer causes increased release of small extracellular vesicles (sEVs) with distinct biological properties. Mechanistically, cholesterol depletion leads to impaired autophagic flux, redirection of autophagosomes to late endosomes, and subsequently increased sEV secretion ...
Jazmine D. W. Yaeger +6 more
wiley +1 more source

