Results 21 to 30 of about 63,367 (249)
Journal of Lipid Research, 2002 The Niemann-Pick C1 (NPC1) protein regulates cholesterol transport from late endosomes-lysosomes to other intracellular compartments. In this article, cholesterol transport to caveolin-1 and caveolin-2 containing compartments, such as the trans-Golgi ...
William S. Garver +5 more
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The importance of caveolin as a target in the prevention and treatment of diabetic cardiomyopathy
Frontiers in Immunology, 2022 The diabetic population has been increasing in the past decades and diabetic cardiomyopathy (DCM), a pathology that is defined by the presence of cardiac remodeling and dysfunction without conventional cardiac risk factors such as hypertension and ...
Weiyi Xia +7 more
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Caveolin-1 Signaling in Lung Fibrosis [PDF]
The Open Rheumatology Journal, 2012 Caveolin-1 is a master regulator of several signaling cascades because it is able to bind to and thereby inhibit members of a variety of kinase families. While associated with caveolae and involved in their generation, caveolin-1 is also present at other sites.
Tourkina, Elena, Hoffman, Stanley
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Sterol Carrier Protein-2 Directly Interacts with Caveolin-1 in Vitro and in Vivo [PDF]
, 2004 HDL-mediated reverse-cholesterol transport as well as phosphoinositide signaling are mediated through plasma membrane microdomains termed caveolae/lipid rafts.
Atshaves, Barbara P. +7 more
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Journal of Pharmacological Sciences, 2008 Caveolin-1 is a principal component of caveolae, invaginations of the plasma membrane that are enriched in cholesterol and sphingolipids. The expression of caveolin-1 has been shown to be tightly correlated to the progression of breast cancer tumors ...
Hua Zhu +4 more
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The caveolin-1 scaffolding domain peptide decreases phosphatidylglycerol levels and inhibits calcium-induced differentiation in mouse keratinocytes. [PDF]
PLoS ONE, 2013 Phospholipase D2 (PLD2) has been found localized in low-density caveolin-rich membrane microdomains. Our previous study suggested that PLD2 and aquaporin 3 (AQP3) interact in these domains to inhibit keratinocyte proliferation and promote differentiation
Haixia Qin, Wendy B Bollag
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The lipoatrophic caveolin-1 deficient mouse model reveals autophagy in mature adipocytes [PDF]
, 2010 Adipose tissue lipoatrophy caused by caveolin gene deletion in mice is not linked to defective adipocyte differentiation. We show that adipose tissue development cannot be rescued by endothelial specific caveolin-1 re-expression, indicating primordial ...
C. Prado +8 more
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Redox Regulation of Signaling Complex between Caveolin-1 and Neuronal Calcium Sensor Recoverin
Biomolecules, 2022 Caveolin-1 is a cholesterol-binding scaffold protein, which is localized in detergent-resistant membrane (DRM) rafts and interacts with components of signal transduction systems, including visual cascade.
Vasiliy I. Vladimirov +14 more
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Biomedicines, 2021 Caveolin-1 overexpression has previously been reported as a marker of endothelial injury in kidney chronic antibody-mediated rejection (c-ABMR), but conclusive evidence supporting its use for daily diagnostic practice is missing.
Alessandro Gambella +10 more
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Journal of Lipid Research, 2010 Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin +12 more
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