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Assessing the Prognostic Value of Cytoplasmic and Stromal Caveolin-1 in Early Triple-Negative Breast Cancer Undergoing Neoadjuvant Chemotherapy. [PDF]

open access: yesInt J Mol Sci
Teruel I   +23 more
europepmc   +1 more source

Caveolin-1, a Determinant of the Fate of MCF-7 Breast Cancer Cells. [PDF]

open access: yesBreast Cancer (Auckl)
Chai T, Yue W, Xu P, Gildea J, Felder R.
europepmc   +1 more source
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Caveolin-1: A promising therapeutic target for diverse diseases.

Current Molecular Pharmacology, 2021
The plasma membrane of eukaryotic cells contains small flask-shaped invaginations known as caveolae that are involved in the regulation of cellular signaling. Caveolin-1 is a 21-24kDa protein localized in the caveolar membrane.
Shivani Gokani, L. Bhatt
semanticscholar   +1 more source

Caveolin‐1 in oncogenic metabolic symbiosis

International Journal of Cancer, 2020
Metabolic phenotypes of cancer cells are heterogeneous and flexible as a tumor mass is a hurriedly evolving system capable of constant adaptation to oxygen and nutrient availability. The exact type of cancer metabolism arises from the combined effects of factors intrinsic to the cancer cells and factors proposed by the tumor microenvironment.
Martina Raudenska   +3 more
openaire   +2 more sources

Atherosclerosis, Caveolae and Caveolin-1

2012
Atherosclerosis is a disease of the blood vessel characterized by the development of an arterial occlusion containing lipid and cellular deposits. Caveolae are 50-100 nm cell surface plasma membrane invaginations that are believed to play an important role in the regulation of cellular signaling and transport of molecules among others. These organelles
Pavlides, Stephanos   +4 more
openaire   +2 more sources

Retinal Caveolin-1 Modulates Neuroprotective Signaling

2015
Caveolin-1 (Cav-1), the scaffolding protein of caveolae, is expressed in several retinal cell types and is associated with ocular pathologies. Cav-1 modulates neuroinflammatory/neuroprotective responses to central nervous system injury. We have shown that loss of Cav-1 results in a blunted cytokine response in retinas challenged with inflammatory ...
Reagan, A.   +6 more
openaire   +3 more sources

Caveolin‐1 expression in Schwann cells

Glia, 1999
Caveolae are non-clathrin-coated invaginations of the plasma membrane, which are present in most cell types. An integral component of caveolae is the caveolin family of related proteins, which not only forms the structural framework of caveolae, but also likely subserves its functional roles, including regulation of signal transduction and cellular ...
Mikol, Daniel D.   +3 more
openaire   +2 more sources

Caveolin-1 in Brain Tumors

2011
Increasing evidences in the last years suggested a possible involvement of caveolin-1 (cav-1) in the biology of brain tumors. In vitro studies on glioma cell lines as well as immuno-phenotyping of primary human gliomas reported that cav-1 expression in brain tumors varies according to the histotype and grade, and could bear prognostic significance in ...
SENETTA, REBECCA, CASSONI, Paola
openaire   +2 more sources

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