Results 71 to 80 of about 24,232,284 (333)

カベオリン異常症における特徴的な骨格筋MRI画像所見に関する検討 [PDF]

, 2019
博士(医学) 甲第702号(主論文の要旨、要約、審査結果の要旨、本文)，著者名:Kumiko IHIGURO・Takahiro NAKAYAMA・Masaru YOSHIOKA・Terumi MURAKAMI・Sachiko KAJINO・Minobu SHICHIJI・Takatoshi SATO・Naomi HINO-FUKUYO・Satoshi KURU・Makiko OSAWA・Satoru NAGATA・Mariko OKUBO・Nobuyuki MURAKAMI・Yukiko K ...
石黒 久美子
core   +2 more sources

Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER–mitochondria communication during the early phase of ER stress

Cell Death and Differentiation, 2018
Close contacts between endoplasmic reticulum and mitochondria enable reciprocal Ca2+ exchange, a key mechanism in the regulation of mitochondrial bioenergetics.
R. Bravo-Sagua, V. Parra, Carolina Ortiz-Sandoval, Mario Navarro-Márquez, Andrea E. Rodríguez, N. Díaz-Valdivia, C. Sanhueza, Camila López-Crisosto, Nasser Tahbaz, B. Rothermel, Joseph A. Hill, M. Cifuentes, T. Simmen, A. Quest, S. Lavandero   +14 more
semanticscholar   +1 more source

Involvement of caveolin-1 in skin diseases

Frontiers in Immunology, 2022
The skin is the outermost layer and largest organ in the human body. Since the skin interfaces with the environment, it has a variety of roles, including providing a protective barrier against external factors, regulating body temperature, and retaining water in the body.
Naoko Takamura, Yukie Yamaguchi
openaire   +3 more sources

Caveolin as a Potential Drug Target for Cardiovascular Protection

Frontiers in Physiology, 2012
Caveolae and caveolin are key players in a number of disease processes. Current research indicates that caveolins play a significant role in cardiovascular disease and dysfunction.
Stephanie L Sellers, Andy eTrane, Pascal N Bernatchez   +2 more
doaj   +1 more source

Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]

, 2010
The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V., Jimenez, Sergio A., Piera-Velazquez, Sonsoles   +2 more
core   +2 more sources

MiR-124-3p attenuates hyperphosphorylation of tau protein-induced apoptosis via caveolin-1-PI3K/Akt/GSK3β pathway in N2a/APP695swe cells

OncoTarget, 2017
Hyperphosphorylation of Tau forming neurofibrillary tangles has been considered as a crucial event in the pathogenesis of Alzheimer's disease (AD). MiR-124-3p belongs to microRNA (miRNA) family and was markedly decreased in AD, however, the functions of ...
Qingmei Kang, Y. Xiang, Dan-guang Li, Jie Liang, Xiong Zhang, Fanlin Zhou, Mengyuan Qiao, Y. Nie, Y. He, J. Cheng, Yu-bing Dai, Y. Li   +11 more
semanticscholar   +1 more source

Sterol Carrier Protein-2 Directly Interacts with Caveolin-1 in Vitro and in Vivo [PDF]

, 2004
HDL-mediated reverse-cholesterol transport as well as phosphoinositide signaling are mediated through plasma membrane microdomains termed caveolae/lipid rafts.
Atshaves, Barbara P., Ball, Judith M., Kier, Ann B., Parr, Rebecca D., Payne, H. Ross, Petrescu, Anca D., Schroeder, Friedhelm, Zhou, Minglong   +7 more
core   +2 more sources

The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells

Oncogene, 2017
N-myc downstream-regulated gene 1 (NDRG1) has been reported to act as a key regulatory molecule in tumor progression-related signaling pathways, especially in tumor metastasis. However, the related mechanism has not been fully discovered yet.
L. Mi, Feng Zhu, Xiao-Mei Yang, Jiaoyang Lu, Y. Zheng, Qing-hua Zhao, X. Wen, A. Lu, Ming Wang, Minhua Zheng, J. Ji, Jing Sun   +11 more
semanticscholar   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Caveolin-1, TGF-β receptor internalization, and the pathogenesis of systemic sclerosis [PDF]

, 2008
PURPOSE OF REVIEW: To review the scientific literature supporting the participation of caveolin-1 in the pathogenesis of tissue fibrosis and the notion that modulation of the caveolin-1 pathway may represent a novel treatment for systemic sclerosis and ...
Del Galdo, Francesco, Jimenez, Sergio A., Lisanti, Michael P.   +2 more
core   +1 more source