Results 151 to 160 of about 1,094 (184)
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Cavin proteins: New players in the caveolae field
Biochimie, 2011Caveolae are specialized lipid microdomains, forming small invaginations in the plasma membrane, known to be implicated in multiple functions including lipid storage, cell signaling and endocytosis. Formation of these wide flask-shaped invaginations is dependent on the expression of a caveolar coat protein, namely caveolin.
Briand, Nolwenn +2 more
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Focus on the role of Caveolin and Cavin protein families in liposarcoma
Differentiation, 2017The identification of ancillary biomarkers useful to improve diagnosis is a major challenge for adipocytic liposarcoma (LPS), the most common type among soft tissue sarcomas affecting adulthood. Recent findings have reported the expression of some proteins belonging to Caveolin and Cavin families as a critical hallmark distinctive of the least ...
Codenotti, Silvia +3 more
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Characterisation of the cavin proteins role in the circadian rhythm [PDF]
, 2022 Caveolae are nanoscale size invaginations of the plasma membrane identified by their unique flask-shape morphology. They are considered to play an important role in lipid metabolism and provide essential mechanosensing and protective capacity to the membrane. The cytosolic coat composed of the cavin family of proteins, namely Cavin1, Cavin2, Cavin3 and
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Cavin-1: caveolae-dependent signalling and cardiovascular disease
Biochemical Society Transactions, 2014Caveolae are curved lipid raft regions rich in cholesterol and sphingolipids found abundantly in vascular endothelial cells, adipocytes, smooth muscle cells and fibroblasts. They are multifunctional organelles with roles in clathrin-independent endocytosis, cholesterol transport, mechanosensing and signal transduction.
Williams, Jamie J.L., Palmer, Timothy M.
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Caveolin and cavin family members: Dual roles in cancer
Biochimie, 2014Caveolae are specialized plasma membrane subdomains with distinct lipid and protein compositions, which play an essential role in cell physiology through regulation of trafficking and signaling functions. The structure and functions of caveolae have been shown to require the proteins caveolins.
Reshu Gupta +2 more
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Cavin 1 function does not follow caveolar morphology
American Journal of Physiology-Cell Physiology, 2015The function of caveolae, small invaginations of the plasma membrane, remains a matter of debate. We discuss endocytosis and compartmentalization of metabolic and signaling pathways. Caveolin 3 (CAV3) and polymerase I and transcript release factor (PTRF) are important proteins that ensure shaping of caveolae in muscle cells.
Timmel, T. +4 more
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Down‐regulation of the cavin family proteins in breast cancer
Journal of Cellular Biochemistry, 2011AbstractCaveolae are abundant membrane domain on the cell surface of many mammalian cell types and are implicated in a wide range of physiological processes. The caveolae structural protein caveolin‐1 is often mutated or deregulated in cancer, and cavin family protein serum deprivation response factor‐related gene product that binds to C‐kinase (SRBC ...
Lin, Bai +9 more
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Increases in endothelial caveolin-1 and cavins correlate with cirrhosis progression
Micron, 2015Caveolin-1 is associated with flat caveolar domains, invaginated smooth plasmalemmal vesicles, and caveolae. Polymerase 1 and transcript release factor (PTRF) (cavin 1) and serum deprivation protein response (SDPR) (cavin 2) are required for the invagination of caveolae, and PRKCDBP (protein kinase C, delta-binding protein; cavin 3) is required for ...
Wataru Ando, Hiroaki Yokomori
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Cavin fever: regulating caveolae
Nature Cell Biology, 2009SDPR is a new regulator of caveolae biogenesis. SDPR overexpression results in increased caveolae size and leads to the formation of caveolae-derived tubules containing Shiga toxin. SDPR may therefore be a membrane curvature-inducing component of caveolae.
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Cavin Family: New Players in the Biology of Caveolae.
International review of cell and molecular biology, 2015Caveolae are specialized small plasma-membrane invaginations that play crucial cellular functions. Two essential protein families are required for caveola formation: membrane caveolin proteins and cytoplasmic cavin proteins. Each family includes members with specific tissue distribution, and their expression is altered under physiological and ...
Nassar, Zeyad D., Parat, Marie-Odile
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