Results 141 to 150 of about 4,643 (177)

CAZyme discovery and design for sweet dreams

Current Opinion in Chemical Biology, 2014
Development of synthetic routes to complex carbohydrates and glyco-conjugates is often hampered by the lack of enzymes with requisite properties or specificities. Indeed, assembly or degradation of carbohydrates requires carbohydrate-active enzymes (CAZymes) able to act on a vast range of glycosidic monomers, oligomers or polymers in a regio-specific ...
Isabelle André, Claire Moulis, Magali Remaud-Simeon   +2 more
exaly   +6 more sources

Innovations in CAZyme gene diversity and its modification for biorefinery applications

Biotechnology Reports (Amsterdam, Netherlands), 2020
For sustainable growth, concept of biorefineries as recourse to the "fossil derived" energy source is important. Here, the Carbohydrate Active enZymes (CAZymes) play decisive role in generation of biofuels and related sugar-based products utilizing lignocellulose as a carbon source.
Anil Kumar Verma, Dixita Chettri
exaly   +4 more sources

Carbohydrate-active enzymes (CAZymes) in the gut microbiome

Nature Reviews Microbiology, 2022
The 1013-1014 microorganisms present in the human gut (collectively known as the human gut microbiota) dedicate substantial percentages of their genomes to the degradation and uptake of carbohydrates, indicating the importance of this class of molecules.
Jacob F. Wardman, Rajneesh K. Bains, Peter Rahfeld, Stephen G. Withers   +3 more
openaire   +2 more sources

Long-Read Metagenomics and CAZyme Discovery

2023
Microorganisms play a primary role in regulating biogeochemical cycles and are a valuable source of enzymes that have biotechnological applications, such as carbohydrate-active enzymes (CAZymes). However, the inability to culture the majority of microorganisms that exist in natural ecosystems restricts access to potentially novel bacteria and ...
Ferrillo, Alessandra, Kobel, Carl Mathias, Vera-Ponce de Leon, Arturo, La Rosa, Sabina Leanti, Kunath, Benoit Josef, Pope, Phillip Byron, Hagen, Live Heldal   +6 more
openaire   +3 more sources

Carbohydrate-Active enZyme (CAZyme) enabled glycoengineering for a sweeter future

Current Opinion in Biotechnology, 2020
One of the stumbling blocks to advance the field of glycobiology has been the difficulty in synthesis of bespoke carbohydrate-based molecules like glycopolymers (e.g. human milk oligosaccharides) and glycoconjugates (e.g. glycosylated monoclonal antibodies).
Chandra Kanth Bandi, Ayushi Agrawal, Shishir P S Chundawat   +2 more
exaly   +4 more sources

The continuing expansion of CAZymes and their families

Current Opinion in Chemical Biology, 2019
Carbohydrate-active enzymes (CAZymes) catalyze the assembly and breakdown of glycans and glycoconjugates. Some have been discovered, studied and exploited for numerous applications long ago. For instance, amylase and invertase were isolated in the second half of the 19th century and lysozyme was the first enzyme whose 3-D structure was determined.
Garron, Marie-Line, Henrissat, Bernard
openaire   +4 more sources

Metagenomics and CAZyme Discovery

2017
Microorganisms play a primary role in regulating biogeochemical cycles and are a valuable source of enzymes that have biotechnological applications, such as carbohydrate-active enzymes (CAZymes). However, the inability to culture the majority of microorganisms that exist in natural ecosystems using common culture-dependent techniques restricts access ...
Kunath, Benoit J., Bremges, Andreas, Weimann, Aaron, McHardy, Alice C., Pope, Phillip B.   +4 more
openaire   +3 more sources

Metagenomics and CAZymes in Rumen: A review

Indian Journal of Animal Nutrition, 2019
Rumen converts lignocellulsic biomass to high quality food by virtue of the diverse microbiota. The composition of rumen ecosystem is shaped up by various factors including diet, individuality, age, geographic region, postfeeding time etc. Earlier culture based techniques could study rumen microbes partially for the cultivable microbes.
Anju Kala, Devki Nandan Kamra, Lal Chandra Chaudhary, Neeta Agarwal   +3 more
openaire   +1 more source

Proteomic Detection of Carbohydrate-Active Enzymes (CAZymes) in Microbial Secretomes

2018
Secretomes from microorganisms growing on biomass contain carbohydrate-active enzymes (CAZymes) of potential biotechnological interest. By analyzing such secretomes, we may discover key enzymes involved in degradation processes and potentially infer the mode-of-action of biomass conversion.
Tina R, Tuveng, Vincent G H, Eijsink, Magnus Ø, Arntzen   +2 more
openaire   +2 more sources

Extending the Chemical Space of CAZymes

2017
Extending the Chemical Space of CAZymes.
Fauré, Régis, Ramillon-Delvolve, Virginie, Ramos, Nuria, Quast, Robert, Bols, Mikael, Barbe, Sophie, André, Isabelle, Montanier, Cédric, Truan, Gilles, Nouaille, Sébastien   +9 more
openaire   +1 more source