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IPGA: A handy integrated prokaryotes genome and pan‐genome analysis web service

open access: yesiMeta, 2022
Pan‐genomics is one of the most powerful means to study genomic variation and obtain a sketch of genes within a defined clade of species. Though there are a lot of computational tools to achieve this, an integrated framework to evaluate their performance 
Dongmei Liu   +9 more
doaj   +2 more sources

First Steps in the Analysis of Prokaryotic Pan-Genomes

open access: yesBioinformatics and Biology Insights, 2020
Pan-genome is defined as the set of orthologous and unique genes of a specific group of organisms. The pan-genome is composed by the core genome, accessory genome, and species- or strain-specific genes.
Sávio Souza Costa   +4 more
doaj   +2 more sources

Comprehensive genomic and computational insights into Brucella suis: pan-genome analysis, evolutionary perspectives, and in-silico vaccine design [PDF]

open access: yesBMC Genomics
Background Brucella suis is a zoonotic intracellular pathogen responsible for brucellosis, mainly in swine and humans. Although numerous genome sequences are publicly available, an integrative genomic analysis combining pan-genome architecture ...
Ghulam Muhammad Sami Ullah Asif   +13 more
doaj   +2 more sources

Pan-Genome Analysis of Staphylococcus aureus Reveals Key Factors Influencing Genomic Plasticity

open access: yesMicrobiology Spectrum, 2022
The massive quantities of bacterial genomic data being generated have facilitated in-depth analyses of bacteria for pan-genomic studies. However, the pan-genome compositions of one species differed significantly between different studies, so we used ...
Na Liu   +4 more
doaj   +3 more sources

PGAP2: A comprehensive toolkit for prokaryotic pan-genome analysis based on fine-grained feature networks [PDF]

open access: yesNature Communications
Pan-genome analysis is a crucial method for studying genomic dynamics. By creating pan-genome maps for prokaryotic organisms, we can gain valuable insights into their genetic diversity and ecological adaptability.
Congfan Bu   +11 more
doaj   +2 more sources

Integrating pan-genome with metagenome for microbial community profiling

open access: yesComputational and Structural Biotechnology Journal, 2021
Advances in sequencing technology have led to the increased availability of genomes and metagenomes, which has greatly facilitated microbial pan-genome and metagenome analysis in the community.
Chaofang Zhong   +3 more
doaj   +1 more source

Oryza pan-genomics: A new foundation for future rice research and improvement

open access: yesCrop Journal, 2021
The wild rice species in the genus Oryza harbor a large amount of genetic diversity that has been untapped for rice improvement. Pan-genomics has revolutionized genomic research in plants. However, rice pan-genomic studies so far have been limited mostly
Chao Huang, Zhuo Chen, Chengzhi Liang
doaj   +1 more source

Sorghum Pan-Genome Explores the Functional Utility for Genomic-Assisted Breeding to Accelerate the Genetic Gain

open access: yesFrontiers in Plant Science, 2021
Sorghum (Sorghum bicolor L.) is a staple food crops in the arid and rainfed production ecologies. Sorghum plays a critical role in resilient farming and is projected as a smart crop to overcome the food and nutritional insecurity in the developing world.
Pradeep Ruperao   +13 more
doaj   +1 more source

Pan-genome inversion index reveals evolutionary insights into the subpopulation structure of Asian rice

open access: yesNature Communications, 2023
Pan-genomes provide useful resources for evolutionary studies, functional genomics and breeding of cultivated plants. Here, the authors report a new rice pan-genome including 73 Asian rice and two wild relatives (Oryza rufipogon and O.
Yong Zhou   +24 more
doaj   +1 more source

Pandora: nucleotide-resolution bacterial pan-genomics with reference graphs

open access: yesGenome Biology, 2021
We present pandora, a novel pan-genome graph structure and algorithms for identifying variants across the full bacterial pan-genome. As much bacterial adaptability hinges on the accessory genome, methods which analyze SNPs in just the core genome have ...
Rachel M. Colquhoun   +10 more
doaj   +1 more source

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