Results 111 to 120 of about 22,655 (236)
The CB1 cannabinoid receptor regulates autophagy in the tibialis anterior skeletal muscle in mice. [PDF]
Sepúlveda C +11 more
europepmc +1 more source
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
CB1 Cannabinoid Receptor is a Target for Neuroprotection in Light Induced Retinal Degeneration. [PDF]
Soliño M +10 more
europepmc +1 more source
ABSTRACT Objective To assess the effect of orally administered cannabidiol (CBD) on TonoVet measured intraocular pressure (IOP) and Schirmer tear test I (STT) in horses. Animal Studied Horse. Procedure This was a masked, randomized, balanced cross‐over study of six healthy adult horses.
Kathryn Diehl +2 more
wiley +1 more source
The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor. [PDF]
Leo LM +9 more
europepmc +1 more source
CB1 Cannabinoid Receptor Location and CRIP1a
CB 1 cannabinoid receptor (CB 1 R) is a Gi/o linked GPCR that influences psychological processes such as mood and memory. Cannabinoid Receptor Interacting Protein (CRIP1a) has been shown to interact with the C‐terminal tail of the CB
Jeremy O'Neal +3 more
openaire +1 more source
Endocannabinoids (eCB) are signaling lipids and became known for their importance in the central nervous system as well as in immune defense. Beneficial effects of eCB are shown in processes of excitotoxic lesion, secondary damage and neuronal plasticity
Kallendrusch, Sonja
core
Serum contents of endocannabinoids are correlated with blood pressure in depressed women.
BACKGROUND: Depression is known to be a risk factor for cardiovascular diseases but the underlying mechanisms remain unclear. Since recent preclinical evidence suggests that endogenous agonists of cannabinoid receptors (endocannabinoids) are involved in ...
Ho, WS V +24 more
core +1 more source
Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model
A new galvanic skin response‐based approach offers a simple method for measuring sweating in the paws of mice. This method is used to demonstrate that cannabinoid CB1 receptors reduce baseline sweating in mice, likely via inhibition of sympathetic acetylcholine release via axonal CB1 receptors.
Natalia Murataeva +3 more
wiley +1 more source

