Results 91 to 100 of about 3,492 (143)

Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MHY11

, 2004
Inv(16)(p13q22) is associated with acute myeloid leukemia subtype M4Eo that is characterized by the presence of myelomonocytic blasts and atypical eosinophils. This chromosomal rearrangement results in the fusion of CBFB and MYH11 genes.
van de Sluis, Bart; id_orcid, Katsuya Shigesada, P Paul Liu, Bart van de Sluis, Liu, P Paul, Shigesada, Katsuya, van de Sluis, Bart   +6 more
core   +1 more source

Inversion of chromosome 16 and uncommon rearrangements of the CBFB and MYH11 genes in therapy-related acute myeloid leukemia: rare events related to DNA-topoisomerase II inhibitors?

, 1998
PURPOSE To evaluate the frequency of inversion of chromosome 16 (inv[16]) and the type of rearrangement of the CBFB and MYH11 genes in therapy-related acute myeloid leukemia (t-AML) and to evaluate a possible relationship to specific types of previous ...
M Dissing, M M Le Beau, J Pedersen-Bjergaard   +2 more
core   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

, 2013
The inv(16)(p13q22)/t(16;16)(p13;q22) in acute myeloid leukemia results in multiple CBFB-MYH11 fusion transcripts, with type A being most frequent. The biologic and prognostic implications of different fusions are unclear.
Curfman, John, Pettenati, Mark J., J. Kohlschmidt, Blum, William, D. Nicolet, M. A. Caligiuri, A. J. Carroll, Bloomfield, Clara D., Carroll, Andrew J., H. Becker, Wu, Yue-Zhong, Larson, Richard A., K. Maharry, Prior, Thomas W., Kohlschmidt, Jessica, Edwards, Colin G., P. D. Cin, Alliance for Clinical Trials in Oncology, Hoellerbauer, Pia, Kolitz, Jonathan E., VOLINIA, Stefano, C. G. Edwards, M. J. Pettenati, G. Marcucci, A. Eisfeld, Maharry, Kati, Schwind, Sebastian, J. Curfman, A. f. Clinical, W. Blum, K. Mrózek, Caligiuri, Michael A., K. H. Metzeler, P. Paschka, J. E. Kolitz, Metzeler, Klaus H., S. Schwind, Eisfeld, Ann-Kathrin, T. W. Prior, Dal Cin, P., Paschka, Peter, R. A. Larson, Marcucci, Guido, Nicolet, Deedra, P. Hoellerbauer, C. D. Bloomfield, Y. Wu, Mrózek, Krzysztof, Becker, Heiko   +48 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Diagnosis and monitoring of CBFB-MYH11-positive acute myeloid leukemia by qualitative and quantitative RT-PCR.

, 2006
Item does not contain fulltextDuring the last decade, many mutations present in myeloid leukemias have been molecularly characterized. Several of these mutations have clear prognostic impact.
Reijden, B.A. van der, Jansen, J.H.
core  

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Age-dependent clinical, molecular, and prognostic differences in patients with AML: a retrospective study

Hematology
Objectives: This study aimed to compare clinical, and molecular features between acute myeloid leukemia (AML) patients aged
Hong Liu, Zhi Li, Jingjing Ma, Yuye Shi, Shandong Tao, Yue Chen, Tingting Ji, Yang Su, Qiuni Chen, Chunling Wang, Liang Yu   +10 more
doaj   +1 more source

A Case of Acute Myeloid Leukemia With inv(16)(p13.1q22);CBFB-MYH11 Presenting With Faggot Cells. [PDF]

Ann Lab Med, 2021
Kim JA, Shin WY, Kim J, Bang HI, Yoon SY, Won JH, Park R.   +6 more
europepmc   +1 more source

Resolving intra-tumor heterogeneity and clonal evolution of core-binding factor acute myeloid leukemia patients with single-cell resolution

Experimental Hematology & Oncology
Reconstructing and understanding intra-tumor heterogeneity, the coexistence of multiple genetically distinct subclones within the tumor of a patient, and tumor development is essential for resolving carcinogenesis and for identifying mechanisms of ...
Raphael Hablesreiter, Paulina M. Strzelecka, Klara Kopp, Natalia Estrada, Anna Dolnik, Marlon Tilgner, Coral Fustero-Torre, Felicitas Thol, Florian H. Heidel, Michael Heuser, Laleh Haghverdi, Lars Bullinger, Friederike Christen, Frederik Damm   +13 more
doaj   +1 more source