Results 211 to 220 of about 88,115 (330)

Rules of engagement: Determinants of chemokine receptor activation and selectivity by CCL27 and CCL28. [PDF]

J Biol Chem
Huang M, Celniker AF, Chitsazi R, Dyer DP, Jansma AL, Kufareva I, Salanga CL, Handel TM.   +7 more
europepmc   +1 more source

A Key Role for Cc Chemokine Receptor 4 in Lipopolysaccharide-Induced Endotoxic Shock [PDF]

, 2000
Yolande Chvatchko, Arlene J. Hoogewerf, Alexandra Meyer, Sami Alouani, Pierre Juillard, Raphaële Buser, François Conquet, Amanda E. I. Proudfoot, Timothy N. C. Wells, Christopher Power   +9 more
openalex   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Chemokines: humble yet mighty players in the tumour microenvironment. [PDF]

Front Immunol
Xavier H, Gireesh AGM, Thomas JA, Suboj P, Suresh A, Biju E, Baby A, Dominic RT, Babykutty S.   +8 more
europepmc   +1 more source

Essential Roles of the CC Chemokine Ligand 3-CC Chemokine Receptor 5 Axis in Bleomycin-Induced Pulmonary Fibrosis through Regulation of Macrophage and Fibrocyte Infiltration [PDF]

, 2007
Yuko Ishida, Akihiko Kimura, Toshikazu Kondo, Takahito Hayashi, Masaya Ueno, Nobuyuki Takakura, Kouji Matsushima, Naofumi Mukaida   +7 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Chemokines as potential biomarkers for predicting the course of COVID-19 - a review of the literature. [PDF]

Front Immunol
Wolszczak-Biedrzycka B, Cieślikiewicz B, Studniarz F, Dąbrowski Ł, Fąs M, Matyszkiewicz-Suchodolska K, Harasimowicz M, Dorf J.   +7 more
europepmc   +1 more source

Involvement of CC Chemokine Receptor 1 and CCL3 in Acute and Chronic Inflammatory Pain in Mice [PDF]

, 2015
María Llorián‐Salvador, Sara González‐Rodríguez, Ana Lastra, María Teresa Fernández‐García, Agustı́n Hidalgo, Luis Menéndez, Ana Baamonde   +6 more
openalex   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

The CCL17/CCL22-CCR4 Axis in Pain Pathogenesis: A Comprehensive Review of Immune-Mediated Mechanisms and Therapeutic Opportunities. [PDF]

Mol Neurobiol
Hasheminia A, Mann S, Liblik K, El-Diasty M.   +3 more
europepmc   +1 more source