Results 51 to 60 of about 125,234 (245)

Transforming Grain‐Boundary Brittle Precipitates to Ductility Pathways in Complex Concentrated Alloy

Advanced Science, EarlyView.
By engineering graded BCC/L12 interfaces, brittle precipitates in a complex concentrated alloy enable sequential deformation, realizing gigapascal strength with >20% elongation to solve the strength‐ductility trade‐off. ABSTRACT Conventional wisdom holds that hard grain‐boundary (GB) precipitates embrittle structural alloys by acting as crack ...
Zhixin Li, Xiao‐Tong Li, Zhaoqi Chen, Yushan Geng, Hao Gong, Sijia Hu, Wenli Song, Wanshun Xia, Chuanzheng Li, Linfa Peng, Yue Fan, Pengfei Guan, Bo Zhang, Weihua Wang, Yong Yang   +14 more
wiley   +1 more source

Atividade forrageira da abelha Apis mellifera sobre as flores da aroeira-vermelha

Agropecuária Catarinense, 2021
O levantamento da abundância e freqüência das abelhas Apis mellifera scutellata, Lepeletier (1836), e as observações do seu comportamento sobre as flores da aroeira-vermelha foram desenvolvidos durante dois ciclos reprodutivos da espécie. Foram coletadas
Maurício Lenzi, Afonso Inácio Orth
doaj  

Astrocytic TIA1‐Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model

Advanced Science, EarlyView.
Astrocytic TIA1‐mediated stress granules (SGs) promote demyelination by sequestering the mRNA of cholesterol synthesis genes. In this model, astrocytic TIA1‐mediated SGs were increased in the optic nerves of EAE mice, leading to the downregulation of cholesterol synthesis genes such as HMGCS1 through sequestration of their mRNA into SGs, which ...
Zheyu Fang, Xin Hua, Ziwei Fan, Jiaxin Zhao, Yuan Zhang, Qiaoyi Zhang, Xi Qu, Shengli Pan, Bingbing Wan, Shiyin Yang, Jia Li, Xu Zhang   +11 more
wiley   +1 more source

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

Çeşitli Koruyucu Maddeler ile Emprenye Edilmiş Sarıçam (Pinus sylvestris L.) Odununda Deniz Şartlarında Oluşan Ağırlık Kayıplarının İncelenmesi

Düzce University Faculty of Forestry Journal of Forestry, 2009
Bu çalışmada, Türkiye denizlerinde 4 ayrı limanda (Trabzon, Bandırma, Finike ve İskenderun), CCA, CCBve Tanalith-E ile emprenyeli sarıçam odun örneklerinde oluşan ağırlık kayıpları belirlenmiştir.
Selim Şen, Mesut Yalçın
doaj  

Machine Learning‐Guided Engineering of Protein Phase Separation Properties in Immune Regulation

Advanced Science, EarlyView.
PScalpel, a machine learning model integrating protein structure extraction, graph contrastive learning, and a genetic algorithm, guides the engineering of protein phase separation ability. It adopts transfer learning methods to provide predictive recommendations for protein phase separation ability changes through single amino acid mutations in a ...
Chenqiu Zhang, Jia Wang, Zhe Wang, Liyan Zhu, Sihui Cai, Luzhi Zhan, Haorui Liang, Yaoxing Wu, Jianqiang Li, Jun Cui   +9 more
wiley   +1 more source

FARELO DE ARROZ INTEGRAL EM RAÇÕES PARA LEITÕES DE 43 A 67 DIAS DE IDADE

Ciência Animal Brasileira, 2012
Foram utilizados 64 leitões, fêmeas e machos castrados, de linhagem comercial, com média de 43 dias de idade e com peso inicial médio de 10,73 ± 1,85 kg, com o objetivo de se avaliar os efeitos da inclusão de farelo de arroz integral (FAI) na ração até ...
Thalles Ribeiro Gomes, Luiz Euquerio de Carvalho, Ednardo Rodrigues Freitas, Rafael Carlos Nepomuceno, Everardo Ayres C. Ellery, Rennan H. Rufino Moreira   +5 more
doaj   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

DIFFERENT VARIETIES OF SPRING BARLEY IN VORONEZH REGION

Зерновое хозяйство России, 2018
Barley varieties cultivated in Voronezh region satisfy the recommendations of Governmental Variety Testing Commission of RF only on 54,7%. Varieties ‘Vakula’ and ‘Priazovsky 9’ occupy 40% of barley wedge area.
T. G. Golova, L. A. Ershova
doaj   +2 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source