Targeting Crimean-Congo hemorrhagic fever virus: computational and MD-driven discovery of Moringa oleifera peptides against the RdRp-embedded OTU protease. [PDF]
Hassam M +4 more
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Co-Circulation of Tick-Borne <i>Bandaviruses</i> and <i>Orthonairoviruses</i> Across Humans, Livestock, and Rats in Pakistan: Serologic Evidence and Public Health Implications. [PDF]
Ammar M +16 more
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Durable humoral immunity and long-term protection induced by a Crimean-Congo hemorrhagic fever virus replicon particle vaccine in mice. [PDF]
Sorvillo TE +11 more
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Seroprevalence of Crimean-Congo Hemorrhagic Fever and Rift Valley Fever Viruses Among Ruminants in Nigeria: A Descriptive Epizootiological Analysis. [PDF]
Ehizibolo DO +23 more
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Cross-Neutralization of Hazara Virus by Convalescent Sera from CCHFV- Infected Individuals
Bakangil Ö., Doymaz M. Z.
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In this study, the hard ticks, whole blood and serum samples collected from small ruminants (sheep and goat) in middle Black Sea region of Turkey where Crimean-Congo hemorrhagic fever (CCHF) human cases were observed in the past years were surveyed for the presence of RNA and specific IgG antibodies from CCFH virus (CCHFV). CCHFV RNA was found in 30 of
Ozan E +2 more
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Favipiravir and Ribavirin protect immunocompetent mice from lethal CCHFV infection
Antiviral Research, 2023Crimean-Congo hemorrhagic fever virus (CCHFV) causes Crimean-Congo hemorrhagic fever (CCHF) in humans with high morbidity and mortality. Currently, there is neither an approved antiviral drug nor a vaccine against CCHFV. In this study, we describe a lethal model of CCHFV infection using a mouse-adapted strain of CCHFV (MA-CCHFV) in adult wild-type male
Thomas Tipih +7 more
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ANIMAL MODELS FOR CCHFV AND BSL-2, BSL-3 SURROGATE MODELS
Scientific Papers Journal VETERINARY SERIES, 2023Crimean-Congo hemorrhagic fever virus (CCHFV) is an important tick-borne human pathogen endemic throughout Asia, Africa and Europe. The pathogenic mechanisms of CCHF are poorly understood, largely due to the dehttps://www.uaiasi.ro/revmvis/index_htm_files/Arth of animal models.
Serban MOROSAN +2 more
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AbstractCrimean‐Congo hemorrhagic fever virus (CCHFV) is classified among top 10 priority pathogens by World Health Organization. CCHFV belongs to Bunyaviridae family and negative sense ssRNA genome composed of three RNA segments: L, M, and S. RNA viruses show higher mutation rate as compared to DNA viruses.
Neha Kaushal, Manoj Baranwal
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